Chronic inhalation of ethylene glycol monoethyl ether affected the reproduction of male rats

2006 ◽  
Vol 164 ◽  
pp. S71
Author(s):  
Rui-Sheng Wang ◽  
Megumi Suda ◽  
Katsumi Ohtani
Keyword(s):  
Ethylene Glycol ◽  
Male Rats ◽  
Monoethyl Ether ◽  
Glycol Monoethyl Ether

Chemoprotection of ethylene glycol monoethyl ether-induced reproductive toxicity in male rats by kolaviron, isolated biflavonoid from Garcinia kola seed

2011 ◽  
Vol 31 (5) ◽  
pp. 506-517 ◽  
Author(s):  
IA Adedara ◽  
EO Farombi
Keyword(s):  
Vitamin E ◽  
Ethylene Glycol ◽  
Protective Effect ◽  
Reproductive Toxicity ◽  
Male Rats ◽  
Antioxidant Systems ◽  
Sod Activity ◽  
Garcinia Kola ◽  
Monoethyl Ether ◽  
Glycol Monoethyl Ether

The present study investigated the protective effect of kolaviron, a biflavonoid from the seed of Garcinia kola, on ethylene glycol monoethyl ether (EGEE)–induced reproductive toxicity in male rats. The protective effect of kolaviron was validated using vitamin E, a standard antioxidant. EGEE was administered at a dose of 200 mg/kg. Other groups of rats were simultaneously treated with kolaviron (100 and 200 mg/kg) and vitamin E (50 mg/kg) for 14 days. EGEE treatment resulted in significant decrease in glutathione (GSH) level, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities but markedly increased the glutathione-S-transferase (GST) and lactate dehydrogenase (LDH) activities in the testes. In the spermatozoa, administration of EGEE caused significant decrease in the activities of CAT, GPx, GST and LDH as well as in the level of GSH but significantly increased SOD activity with concomitant increase in hydrogen peroxide and malondialdehyde levels in both testes and spermatozoa. EGEE-exposed rats showed marked testicular degeneration with concomitant decrease in spermatozoa quantity and quality. Overall, EGEE causes reproductive dysfunction in rats by altering antioxidant systems in the testes and spermatozoa. Kolaviron or vitamin E exhibited protective effects against EGEE-induced male reproductive toxicity by enhancement of antioxidant status and improvement in spermatozoa quantity and quality.

Decreased formation of ethoxyacetic acid from ethylene glycol monoethyl ether and reduced atrophy of testes in male rats upon combined administration with toluene and xylene

1999 ◽  
Vol 104 (1-2) ◽  
pp. 143-150 ◽  
Author(s):  
Woon-Gye Chung ◽  
Il-Je Yu ◽  
Chang-Shin Park ◽  
Kyung-Hoon Lee ◽  
Hyung-Keun Roh ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Male Rats ◽  
Monoethyl Ether ◽  
Combined Administration ◽  
Glycol Monoethyl Ether

Ethylene glycol monoethyl ether (EGME) adsorption by organic matter (OM)-clay complexes: Dependence on the OM Type

2019 ◽  
Vol 168 ◽  
pp. 340-347 ◽  
Author(s):  
Hongling Bu ◽  
Dong Liu ◽  
Peng Yuan ◽  
Xiang Zhou ◽  
Hongmei Liu ◽  
...  
Keyword(s):  
Organic Matter ◽  
Ethylene Glycol ◽  
Monoethyl Ether ◽  
Glycol Monoethyl Ether

scholarly journals Effect of ethylene glycol monoethyl ether on the spermatogenesis in pubertal and adult rats

2001 ◽  
Vol 2 (1) ◽  
pp. 47 ◽  
Author(s):  
Chang Yong Yoon ◽  
Choong Man Hong ◽  
Ji Young Song ◽  
Yong Yeon Cho ◽  
Kwang Sik Choi ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Adult Rats ◽  
Monoethyl Ether ◽  
Glycol Monoethyl Ether
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