Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death

2013 ◽  
Vol 221 (3) ◽  
pp. 176-184 ◽  
Author(s):  
Greg M. Landry ◽  
Cody L. Dunning ◽  
Taylor Conrad ◽  
Mallory J. Hitt ◽  
Kenneth E. McMartin
Keyword(s):  
Cell Death ◽  
Proximal Tubule ◽  
Mitochondrial Dysfunction ◽  
Succinate Dehydrogenase ◽  
Dehydrogenase Activity ◽  
Succinate Dehydrogenase Activity ◽  
Proximal Tubule Cells ◽  
Diglycolic Acid ◽  
Tubule Cells ◽  
Human Proximal Tubule

Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells

2007 ◽  
Vol 22 (6) ◽  
pp. 798-803 ◽  
Author(s):  
Gerald Schwerdt ◽  
Antje Kirchhoff ◽  
Ruth Freudinger ◽  
Brigitte Wollny ◽  
Andreas Benesic ◽  
...  
Keyword(s):  
Cell Death ◽  
Proximal Tubule ◽  
Proximal Tubule Cells ◽  
Tubule Cells ◽  
Human Proximal Tubule

Heterogeneity in the amount of ionic cadmium necessary to elicit cell death in independent cultures of human proximal tubule cells

1994 ◽  
Vol 70 (2) ◽  
pp. 185-191 ◽  
Author(s):  
Mary Ann Sens ◽  
Debra J. Hazen-Martin ◽  
John E. Bylander ◽  
Donald A. Sens
Keyword(s):  
Cell Death ◽  
Proximal Tubule ◽  
Proximal Tubule Cells ◽  
Tubule Cells ◽  
Human Proximal Tubule

scholarly journals Comparison of diglycolic acid exposure to human proximal tubule cells in vitro and rat kidneys in vivo

2017 ◽  
Vol 4 ◽  
pp. 342-347 ◽  
Author(s):  
Miriam E. Mossoba ◽  
Sanah Vohra ◽  
Howard Toomer ◽  
Shelia Pugh-Bishop ◽  
Zachary Keltner ◽  
...  
Keyword(s):  
Proximal Tubule ◽  
Acid Exposure ◽  
Proximal Tubule Cells ◽  
Diglycolic Acid ◽  
Tubule Cells ◽  
Human Proximal Tubule ◽  
Rat Kidneys

scholarly journals Electrophysiology and ultrastructure of cultured human proximal tubule cells

1988 ◽  
Vol 33 (2) ◽  
pp. 508-516 ◽  
Author(s):  
John G. Blackburn ◽  
Debra J. Hazen-Martin ◽  
Carol J. Detrisac ◽  
Donald A. Sens
Keyword(s):  
Proximal Tubule ◽  
Proximal Tubule Cells ◽  
Tubule Cells ◽  
Human Proximal Tubule

scholarly journals Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently

Cells ◽  
2015 ◽  
Vol 4 (3) ◽  
pp. 234-252 ◽  
Author(s):  
Carolien Schophuizen ◽  
Joost Hoenderop ◽  
Rosalinde Masereeuw ◽  
Lambert Heuvel
Keyword(s):  
Proximal Tubule ◽  
Organic Cation ◽  
Uremic Toxins ◽  
Proximal Tubule Cells ◽  
Cation Uptake ◽  
Tubule Cells ◽  
Human Proximal Tubule
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