Potential role of HSP90 in mediating the interactions between estrogen receptor (ER) and aryl hydrocarbon receptor (AhR) signaling pathways

2014 ◽  
Vol 226 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Ziwei Chang ◽  
Ming Lu ◽  
So-Sun Kim ◽  
Jang-Su Park
Keyword(s):  
Estrogen Receptor ◽  
Aryl Hydrocarbon Receptor ◽  
Signaling Pathways ◽  
Potential Role ◽  
Aryl Hydrocarbon

scholarly journals The Aryl Hydrocarbon Receptor Relays Metabolic Signals to Promote Cellular Regeneration

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Fanny L. Casado
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Transcription Factor ◽  
Regenerative Medicine ◽  
Aryl Hydrocarbon Receptor ◽  
Signaling Pathways ◽  
Metabolic Efficiency ◽  
Aryl Hydrocarbon ◽  
Cellular Regeneration

While sensing the cell environment, the aryl hydrocarbon receptor (AHR) interacts with different pathways involved in cellular homeostasis. This review summarizes evidence suggesting that cellular regeneration in the context of aging and diseases can be modulated by AHR signaling on stem cells. New insights connect orphaned observations into AHR interactions with critical signaling pathways such as WNT to propose a role of this ligand-activated transcription factor in the modulation of cellular regeneration by altering pathways that nurture cellular expansion such as changes in the metabolic efficiency rather than by directly altering cell cycling, proliferation, or cell death. Targeting the AHR to promote regeneration might prove to be a useful strategy to avoid unbalanced disruptions of homeostasis that may promote disease and also provide biological rationale for potential regenerative medicine approaches.

Potential role of aryl hydrocarbon receptor signaling in childhood obesity

2020 ◽  
Vol 1865 (8) ◽  
pp. 158714 ◽  
Author(s):  
Nancy N. Shahin ◽  
Ghada T. Abd-Elwahab ◽  
Afaf A. Tawfiq ◽  
Hanan M. Abdelgawad
Keyword(s):  
Childhood Obesity ◽  
Aryl Hydrocarbon Receptor ◽  
Potential Role ◽  
Receptor Signaling ◽  
Aryl Hydrocarbon

Role of the Aryl Hydrocarbon Receptor (AhR) in Mediating the Effects of Coffee in the Colon

2021 ◽  
pp. 2100539
Author(s):  
Robert S. Chapkin ◽  
Laurie A. Davidson ◽  
Hyejin Park ◽  
Un‐Ho Jin ◽  
Yang‐Yi Fan ◽  
...  
Keyword(s):  
Aryl Hydrocarbon Receptor ◽  
Aryl Hydrocarbon
Sign in / Sign up

Export Citation Format

Share Document