scholarly journals Cerebral Blood Flow Characteristics and Biometry in Fetuses Undergoing Prenatal Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome

2010 ◽  
Vol 36 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Doff B. McElhinney ◽  
Carol B. Benson ◽  
David W. Brown ◽  
Louise E. Wilkins-Haug ◽  
Audrey C. Marshall ◽  
...  
2010 ◽  
Vol 106 (12) ◽  
pp. 1792-1797 ◽  
Author(s):  
Doff B. McElhinney ◽  
Melanie Vogel ◽  
Carol B. Benson ◽  
Audrey C. Marshall ◽  
Louise E. Wilkins-Haug ◽  
...  

2013 ◽  
Vol 23 (5) ◽  
pp. 675-681 ◽  
Author(s):  
Pablo Marantz ◽  
Horacio Aiello ◽  
Sofía Grinenco ◽  
Gustavo Izbizky ◽  
Gabriela Peña ◽  
...  

AbstractObjectivesFoetal aortic valvuloplasty has been proposed as a strategy to improve left heart growth and function in foetuses with severe aortic stenosis at risk of progression to hypoplastic left heart syndrome. We report our experience with this intervention.Methods and resultsBetween 2005 and 2010, five foetuses with aortic stenosis and at risk of progression to hypoplastic left heart syndrome underwent ultrasound-guided percutaneous foetal aortic valvuloplasty. There were no associated maternal complications or foetal demise. In one case, the pregnancy was terminated a couple of weeks after the intervention, one foetus evolved to hypoplastic left heart syndrome, and three did not.ConclusionsFoetal aortic valvuloplasty seems to be a safe and feasible procedure. It has been reported that it has the potential to prevent progression to hypoplastic left heart syndrome in selected foetuses with severe aortic stenosis. Further investigation regarding physiological and clinical aspects of this disease both prenatally and postnatally will probably allow to improve therapeutic strategies and clinical outcome.


2015 ◽  
Vol 17 (S1) ◽  
Author(s):  
Philip Wegner ◽  
Michael Jerosch-Herold ◽  
Christopher Hart ◽  
Eileen Pardun ◽  
Hans-Heiner Kramer ◽  
...  

2016 ◽  
Vol 36 (5) ◽  
pp. 48-55
Author(s):  
Sharon L. Cheatham ◽  
Grace M. Deyo

Hybrid stage I palliation combines cardiothoracic surgery and interventional transcatheter procedures for treatment of hypoplastic left heart syndrome. The approach is an alternative to the Norwood procedure, the traditional first stage of surgical palliation. Hybrid stage I palliation involves placing bilateral branch pulmonary artery bands and a patent ductus arteriosus stent through a median sternotomy, performed without cardiopulmonary bypass. The purpose of the bands is to control blood flow to the lungs and protect the pulmonary bed while the stent sustains systemic cardiac output. A balloon atrial septostomy is performed to create an atrial septal defect for unobstructed blood flow from the left atrium to the right atrium. The second stage of palliative surgery is the comprehensive stage II, which incorporates removal of the stent and pulmonary artery bands, atrial septectomy, anastomosis of the diminutive ascending aorta to the main pulmonary artery, aortic arch augmentation, and bidirectional cavopulmonary anastomosis. The traditional Fontan procedure completes the series of palliation.


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