UP-02.098 The Novel AKT-Inhibitor AZD5363 Abrogates Androgen-Receptor Signaling and Delays Hormone-Sensitive and Castration-Resistant Prostate Cancer Progression in vivo

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S293
Author(s):  
C. Thomas ◽  
F. Lamoureux ◽  
C. Crafter ◽  
B. Davies ◽  
A. Zoubeidi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Progression ◽  
The Novel ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Akt Inhibitor ◽  
Androgen Receptor Signaling ◽  
Castration Resistant ◽  
Hormone Sensitive

Synergistic Targeting of PI3K/AKT Pathway and Androgen Receptor Axis Significantly Delays Castration-Resistant Prostate Cancer Progression In Vivo

2013 ◽  
Vol 12 (11) ◽  
pp. 2342-2355 ◽  
Author(s):  
Christian Thomas ◽  
Francois Lamoureux ◽  
Claire Crafter ◽  
Barry R. Davies ◽  
Eliana Beraldi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Progression ◽  
Akt Pathway ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

318 SYNERGISTIC TARGETING OF PI3K/AKT-PATHWAY AND ANDROGEN-RECEPTOR AXIS SIGNIFICANTLY DELAYS CASTRATION-RESISTANT PROSTATE CANCER PROGRESSION IN VIVO

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Christian Thomas ◽  
Francois Lamoureux ◽  
Claire Crafter ◽  
Barry Davies ◽  
Eliana Beraldi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Progression ◽  
Akt Pathway ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

scholarly journals Inhibition of Hedgehog and Androgen Receptor Signaling Pathways Produced Synergistic Suppression of Castration-Resistant Prostate Cancer Progression

2013 ◽  
Vol 11 (11) ◽  
pp. 1448-1461 ◽  
Author(s):  
Pramod S. Gowda ◽  
Jianhong D. Deng ◽  
Sweta Mishra ◽  
Abhik Bandyopadhyay ◽  
Sitai Liang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Signaling Pathways ◽  
Cancer Progression ◽  
Receptor Signaling ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Androgen Receptor Signaling ◽  
Castration Resistant

scholarly journals Transcription Factor Stat5 Knockdown Enhances Androgen Receptor Degradation and Delays Castration-Resistant Prostate Cancer Progression In vivo

2011 ◽  
Vol 10 (2) ◽  
pp. 347-359 ◽  
Author(s):  
Christian Thomas ◽  
Amina Zoubeidi ◽  
Hidetoshi Kuruma ◽  
Ladan Fazli ◽  
Francois Lamoureux ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transcription Factor ◽  
Androgen Receptor ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

ASC-J9® suppresses castration resistant prostate cancer progression via degrading the enzalutamide-induced androgen receptor mutant AR-F876L

2016 ◽  
Vol 379 (1) ◽  
pp. 154-160 ◽  
Author(s):  
Ronghao Wang ◽  
Wanying Lin ◽  
Changyi Lin ◽  
Lei Li ◽  
Yin Sun ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant ◽  
Receptor Mutant

scholarly journals Downregulation of LOX promotes castration-resistant prostate cancer progression via IGFBP3

2021 ◽  
Vol 12 (24) ◽  
pp. 7349-7357
Author(s):  
Xuanrong Chen ◽  
Yi Shao ◽  
Wanqing Wei ◽  
Haishan Shen ◽  
Yang Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

scholarly journals Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression

Oncotarget ◽  
2016 ◽  
Vol 7 (38) ◽  
pp. 61955-61969 ◽  
Author(s):  
Jingbo Qiao ◽  
Magdalena M. Grabowska ◽  
Ingrid S. Forestier-Roman ◽  
Janni Mirosevich ◽  
Thomas C. Case ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant
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