scholarly journals Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Virology ◽  
2019 ◽  
Vol 526 ◽  
pp. 180-188 ◽  
Author(s):  
Nigel Bourne ◽  
Brianne N. Banasik ◽  
Clarice L. Perry ◽  
Aaron L. Miller ◽  
Mellodee White ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Guinea Pigs ◽  
Simplex Virus

Outcome of herpes simplex virus type 2 infection in guinea pigs

1992 ◽  
Vol 36 (4) ◽  
pp. 303-308 ◽  
Author(s):  
Sandra L. Fowler ◽  
Christopher J. Harrison ◽  
Martin G. Myers ◽  
Lawrence R. Stanberry
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Guinea Pigs ◽  
Simplex Virus

scholarly journals Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs

2015 ◽  
Vol 24 (1) ◽  
pp. 19-27 ◽  
Author(s):  
David I Bernstein ◽  
Fernando J Bravo ◽  
Derek A Pullum ◽  
Hui Shen ◽  
Mei Wang ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Genital Herpes ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Guinea Pigs ◽  
Simplex Virus

scholarly journals Long-Term Presence of Virus-Specific Plasma Cells in Sensory Ganglia and Spinal Cord following Intravaginal Inoculation of Herpes Simplex Virus Type 2

2005 ◽  
Vol 79 (17) ◽  
pp. 11537-11540 ◽  
Author(s):  
Gregg N. Milligan ◽  
Michael G. Meador ◽  
Chin-Fun Chu ◽  
Christal G. Young ◽  
Talitha L. Martin ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Guinea Pigs ◽  
Plasma Cells ◽  
Neuronal Tissues ◽  
Simplex Virus

ABSTRACT The tissue sites of long-term herpes simplex virus type 2 (HSV-2)-specific antibody production in mice and guinea pigs were identified. In addition to secondary lymphoid tissue and bone marrow, HSV-specific plasma cells were detected in spinal cords of mice up to 10 months after intravaginal inoculation with a thymidine kinase-deficient HSV-2 strain and in lumbosacral ganglia and spinal cords of guinea pigs inoculated with HSV-2 strain MS. The long-term retention of virus-specific plasma cells in the peripheral and central nervous systems following HSV infection may be important for resistance to reinfection of neuronal tissues or may play a role in modulation of reactivation from latency.

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