Complications of Sigmoid Sinus Transvenous Occlusion for the Endovascular Treatment of Dural Arteriovenous Shunts with Emphasis on Inner Ear Dysfunction

2016 ◽  
Vol 88 ◽  
pp. 41-48 ◽  
Author(s):  
Gerasimos Baltsavias ◽  
Johannes Richter ◽  
Stefan Hegemann ◽  
Anton Valavanis
Keyword(s):  
Endovascular Treatment ◽  
Inner Ear ◽  
Sigmoid Sinus ◽  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts ◽  
Inner Ear Dysfunction

scholarly journals Treatment of Intracranial Venous Occlusive Disease with Sigmoid Sinus Angioplasty and Stent Placement in a Case of Infantile Multifocal Dural Arteriovenous Shunts

2001 ◽  
Vol 7 (1) ◽  
pp. 51-60 ◽  
Author(s):  
P. Vilela ◽  
R. Willinsky ◽  
K. terBrugge
Keyword(s):  
Stent Placement ◽  
Venous Pressure ◽  
Jugular Bulb ◽  
Sigmoid Sinus ◽  
Occlusive Disease ◽  
Dural Sinus ◽  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts ◽  
The Right ◽  
Transvenous Approach

The infantile dural arteriovenous shunts are multifocal involving different dural sinuses and progress to an occlusive venopathy with sigmoid sinus and/or jugular bulb stenosis and subsequent occlusion. We report a successful angioplasty and stent placement of a sigmoid sinus — jugular bulb stenosis due to venous occlusive disease in a patient with infantile dural arteriovenous shunts. A five-year-old patient presented with status epilepticus due to severe venous congestive encephalopathy. The angiogram revealed multifocal dural arteriovenous shunts, occlusion of the right sigmoid sinus, absence of cavernous sinuses and significant stenosis of the left sigmoid sinus — jugular bulb. By transvenous approach, percutaneous transluminal balloon angioplasty and stent placement of the stenosed left sigmoid sinus — jugular bulb segment was performed. This resulted in a significant decrease of the venous pressure gradient across the stenosis and allowed a dramatic clinical recovery. Dural sinus angioplasty and stent placement appears to be a safe and effective procedure and should be considered in the treatment of the venous occlusive disease associated with infantile dural arteriovenous shunts.

Endovascular Treatment of Dural Arteriovenous Shunts

2004 ◽  
Vol 4 (4) ◽  
pp. 176-194
Author(s):  
A SHAIBANI ◽  
R PARKINSON ◽  
E RUSSELL ◽  
B BENDOK ◽  
R BERNSTEIN ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts

scholarly journals Fully automated preoperative segmentation of temporal bone structures from clinical CT scans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
C. A. Neves ◽  
E. D. Tran ◽  
I. M. Kessler ◽  
N. H. Blevins
Keyword(s):  
Facial Nerve ◽  
Inner Ear ◽  
Temporal Bone ◽  
Hausdorff Distance ◽  
Sigmoid Sinus ◽  
Ct Scans ◽  
Automated Segmentation ◽  
Dice Coefficient ◽  
Lateral Skull Base ◽  
End To End

AbstractMiddle- and inner-ear surgery is a vital treatment option in hearing loss, infections, and tumors of the lateral skull base. Segmentation of otologic structures from computed tomography (CT) has many potential applications for improving surgical planning but can be an arduous and time-consuming task. We propose an end-to-end solution for the automated segmentation of temporal bone CT using convolutional neural networks (CNN). Using 150 manually segmented CT scans, a comparison of 3 CNN models (AH-Net, U-Net, ResNet) was conducted to compare Dice coefficient, Hausdorff distance, and speed of segmentation of the inner ear, ossicles, facial nerve and sigmoid sinus. Using AH-Net, the Dice coefficient was 0.91 for the inner ear; 0.85 for the ossicles; 0.75 for the facial nerve; and 0.86 for the sigmoid sinus. The average Hausdorff distance was 0.25, 0.21, 0.24 and 0.45 mm, respectively. Blinded experts assessed the accuracy of both techniques, and there was no statistical difference between the ratings for the two methods (p = 0.93). Objective and subjective assessment confirm good correlation between automated segmentation of otologic structures and manual segmentation performed by a specialist. This end-to-end automated segmentation pipeline can help to advance the systematic application of augmented reality, simulation, and automation in otologic procedures.

Association of distinct intracranial pial and dural arteriovenous shunts

2001 ◽  
Vol 43 (9) ◽  
pp. 770-777 ◽  
Author(s):  
P. Vilela ◽  
K. terBrugge ◽  
R. Willinsky
Keyword(s):  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts

scholarly journals Clinical and Angiographic Characteristics of Multiple Dural Arteriovenous Shunts

2012 ◽  
Vol 33 (9) ◽  
pp. 1691-1695 ◽  
Author(s):  
S.Y. Ha ◽  
Y.S. Kwon ◽  
B.M. Kim ◽  
D.I. Kim ◽  
D.J. Kim
Keyword(s):  
Arteriovenous Shunts ◽  
Dural Arteriovenous Shunts

scholarly journals Tinnitus and Other Auditory Problems – Occupational Noise Exposure below Risk Limits May Cause Inner Ear Dysfunction

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e97377 ◽  
Author(s):  
Ann-Cathrine Lindblad ◽  
Ulf Rosenhall ◽  
Åke Olofsson ◽  
Björn Hagerman
Keyword(s):  
Inner Ear ◽  
Noise Exposure ◽  
Occupational Noise ◽  
Occupational Noise Exposure ◽  
Risk Limits ◽  
Inner Ear Dysfunction

scholarly journals Inner ear is a target for insulin signaling and insulin resistance: evidence from mice and auditory HEI-OC1 cells

2020 ◽  
Vol 8 (1) ◽  
pp. e000820 ◽  
Author(s):  
Ann-Ki Pålbrink ◽  
Franziska Kopietz ◽  
Björn Morén ◽  
René In 't Zandt ◽  
Federico Kalinec ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Protein Kinase ◽  
Inner Ear ◽  
Insulin Signaling ◽  
Organ Of Corti ◽  
Target Tissue ◽  
Dependent Manner ◽  
The Impact ◽  
Rate Limiting ◽  
Inner Ear Dysfunction

ObjectiveThe mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to investigate whether the organ of Corti could be a target tissue for insulin signaling using auditory House Ear Institute-Organ of Corti 1 (HEI-OC1) cells as an in vitro model.MethodsHigh fat diet (HFD) fed C57BL/6J mice were used as a model to study the impact of insulin resistance on the inner ear. In one study, 12 C57BL/6J mice were fed either control diet or HFD and the size of the inner ear endolymphatic fluid compartment (EFC) was measured after 30 days using MRI and gadolinium contrast as a read-out. In another study, the size of the inner ear EFC was evaluated in eight C57BL/6J mice both before and after HFD feeding, with the same techniques. HEI-OC1 auditory cells were used as a model to investigate insulin signaling in organ of Corti cells.ResultsHFD feeding induced an expansion of the EFC in C57BL/6J mice, a hallmark of inner ear dysfunction. Insulin also induced phosphorylation of protein kinase B (PKB/Akt) at Ser473, in a PI3-kinase-dependent manner. The phosphorylation of PKB was inhibited by isoproterenol and IBMX, a general phosphodiesterase (PDE) inhibitor. PDE1B, PDE4D and the insulin-sensitive PDE3B were found expressed and catalytically active in HEI-OC1 cells. Insulin decreased and AICAR, an activator of AMP-activated protein kinase, increased the phosphorylation at the inhibitory Ser79 of acetyl-CoA carboxylase, the rate-limiting enzyme in de novo lipogenesis. Furthermore, the activity of hormone-sensitive lipase, the rate-limiting enzyme in lipolysis, was detected in HEI-OC1 cells.ConclusionsThe organ of Corti could be a target tissue for insulin action, and inner ear insulin resistance might contribute to the association between diabetes and inner ear dysfunction.

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