A Physiologically Based Pharmacokinetic Model of Ertapenem in Pediatric Patients With Renal Impairment

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2020.06.010 ◽

2020 ◽

Vol 109 (9) ◽

pp. 2909-2918

Author(s):

Lingling Ye ◽

Meng Ke ◽

Xiang You ◽

Pinfang Huang ◽

Cuihong Lin

Keyword(s):

Renal Impairment ◽

Pharmacokinetic Model ◽

Pediatric Patients ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically Based Pharmacokinetic Model of Renally Cleared Antibacterial Drugs in Chinese Renal Impairment Patients

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2258 ◽

2020 ◽

Author(s):

Cheng Cui ◽

Xiaobei Li ◽

Hao Liang ◽

Zhe Hou ◽

Siqi Tu ◽

...

Keyword(s):

Renal Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Antibacterial Drugs ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2181 ◽

2019 ◽

Vol 40 (5-6) ◽

pp. 176-187

Author(s):

Kentaro Konishi ◽

Tsuyoshi Minematsu ◽

Yasuhisa Nagasaka ◽

Kenji Tabata

Keyword(s):

Renal Impairment ◽

Pharmacokinetic Model ◽

Severe Renal Impairment ◽

Plasma Concentrations ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Development of a Physiologically Based Pharmacokinetic Model for Prediction of Pramipexole Pharmacokinetics in Parkinson's Disease Patients With Renal Impairment

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1593 ◽

2020 ◽

Vol 60 (8) ◽

pp. 999-1010 ◽

Author(s):

Xiang You ◽

Wanhong Wu ◽

Jing Xu ◽

Zheng Jiao ◽

Meng Ke ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Renal Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment

Translational and Clinical Pharmacology ◽

10.12793/tcp.2019.27.3.107 ◽

2019 ◽

Vol 27 (3) ◽

pp. 107 ◽

Author(s):

Sumin Yoon ◽

Sojeong Yi ◽

Su-jin Rhee ◽

Hyun A Lee ◽

Yun Kim ◽

...

Keyword(s):

Renal Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Asian Children ◽

Physiologically Based

Download Full-text

A GFR-Based Method to Predict the Effect of Renal Impairment on the Exposure or Clearance of Renally Excreted Drugs: A Comparative Study Between a Simple GFR Method and a Physiologically Based Pharmacokinetic Model

Drugs in R&D ◽

10.1007/s40268-020-00327-y ◽

2020 ◽

Vol 20 (4) ◽

pp. 377-387

Author(s):

Iftekhar Mahmood

Keyword(s):

Renal Impairment ◽

Comparative Study ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Developing a physiologically based pharmacokinetic model of apixaban to predict scenarios of drug‐drug interactions, renal impairment and pediatric populations

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14743 ◽

2021 ◽

Author(s):

Ruijuan Xu ◽

Hong Tang ◽

Lin Chen ◽

Weihong Ge ◽

Jin Yang

Keyword(s):

Renal Impairment ◽

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pediatric Populations

Download Full-text

A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2016.06.026 ◽

2016 ◽

Vol 105 (10) ◽

pp. 3205-3213 ◽

Author(s):

Wen Lin ◽

Tycho Heimbach ◽

Jay Prakash Jain ◽

Rakesh Awasthi ◽

Kamal Hamed ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Pediatric Patients ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

Download Full-text

Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Download Full-text