scholarly journals Minimally invasive surgical approaches for temporal lobe epilepsy

2015 ◽  
Vol 47 ◽  
pp. 24-33 ◽  
Author(s):  
Edward F. Chang ◽  
Dario J. Englot ◽  
Sumeet Vadera
Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Jeffrey W Fuchs ◽  
Nathan A Shlobin ◽  
Benjamin Hopkins ◽  
Zehra Husain ◽  
Michael Cloney ◽  
...  

Abstract INTRODUCTION With the advent of minimally invasive surgical approaches for medically refractory epilepsy, we now have the ability to target specific epileptogenic foci with great precision. Previous studies have recognized the importance of complete resection of malformations of cortical development (MCD) in the success of epilepsy surgery. However, many of these lesions escape detection using standard epilepsy protocol MR imaging. This study seeks to evaluate the concurrence of radiographic and histopathologic findings of MCD in patients with refractory temporal lobe epilepsy (TLE) and describe the predictive value of interictal scalp EEG findings in the detection of MCD in an effort to inform surgical decision-making processes. METHODS We retrospectively identified 34 patients who underwent surgical resection for treatment of medically refractory TLE over a 10 yr period at Northwestern University. Preoperative MRI reports, VEEG reports, and postoperative surgical pathology reports were used to correlate radiographic findings of MCD with histopathologic findings of MCD and identify the predictive value of scalp video EEG (VEEG) abnormalities in the detection of MCD. RESULTS We found that 66.7% of focal cortical dysplasias (FCD) identified on pathology and all cases of histopathologically confirmed mild MCD were missed on preoperative MRI. The finding of a rhythmic or continuous interictal abnormality on preoperative VEEG corresponded to a sensitivity of 73.1% and a specificity of 62.5% in detecting either FCD or mild MCD. Of the patients who had a missed FCD on MRI, 80% had continuous or rhythmic interictal abnormalities on EEG. CONCLUSION MCDs are highly prevalent in medically refractory TLE and many of these MCDs are missed on preoperative MRI. The presence of a continuous and/or rhythmic interictal abnormality on scalp VEEG is suggestive of underlying MCD. The presence of one or both of these interictal findings may support the value of performing an intracranial EEG procedure prior to employing an ultraprecise minimally invasive surgical treatment option such as laser ablation.


2018 ◽  
Vol 27 (2) ◽  
pp. 303-318 ◽  
Author(s):  
Jean F. Salem ◽  
Sriharsha Gummadi ◽  
John H. Marks

2013 ◽  
Vol 79 (10) ◽  
pp. 968-972 ◽  
Author(s):  
Christopher Armstrong ◽  
Alana Gebhart ◽  
Brian R. Smith ◽  
Ninh T. Nguyen

Benign gastric tumors in a prepyloric location or within 3 cm adjacent of the gastroesophageal junction (GEJ) are often challenging to resect using minimally invasive surgical techniques. The aim of this study was to examine the outcomes of patients who underwent minimally invasive enucleation or resection of benign gastric tumors at these difficult locations. The charts of patients undergoing minimally invasive resection of benign-appearing submucosal gastric tumors between June 2001 and December 2012 were reviewed. Data on tumor size and location, type of minimally invasive surgical resection, perioperative complications, 90-day mortality, pathology, and recurrence were collected. A total of 70 consecutive patients underwent laparoscopic resection of benign-appearing submucosal gastric tumors; there were 24 patients with lesions close to the GEJ and nine patients with lesions close to the prepyloric region. All lesions were successfully resected laparoscopically. For prepyloric tumors, surgical approaches included enucleation (n = 1), wedge resection (n = 2), and distal gastrectomy with reconstruction (n = 6). For tumors close to the GEJ, surgical approaches included enucleation (n = 16), wedge resection (n = 3), and esophagogastrectomy (n = 5). Complications in this series of 33 patients included late strictures requiring endoscopic dilation in three patients who underwent esophagogastrectomy. The 90-day mortality rate was zero. There were no recurrences over a mean follow-up of 15 months (range, 1 to 86 months). Minimally invasive enucleation or formal anatomic resection of submucosal tumors located adjacent to the GEJ or at the prepyloric region is safe and carries a low risk for tumor recurrence. Submucosal gastric lesions adjacent to the GEJ are amenable to laparoscopic enucleation or wedge resection unless they extend proximally into the esophagus. Prepyloric lesions often require formal anatomic resection with reconstruction.


2017 ◽  
Vol 97 (2) ◽  
pp. 249-264 ◽  
Author(s):  
Sepideh Gholami ◽  
Michael R. Cassidy ◽  
Vivian E. Strong

Sign in / Sign up

Export Citation Format

Share Document