Long-term outcome in a sample of underprivileged patients with psychogenic nonepileptic seizures (PNES) living in Argentina

Outcome Information ◽

Nonepileptic Seizures ◽

The Impact

The scope of research into long-term outcomes of psychogenic nonepileptic seizures (PNES) has broadened in recent years, to take into account of social, economic, psychiatric, and other outcome measures. The quantity of long-term outcome information remains limited, to a great extent because of practical difficulties in obtaining good long-term outcome information in this patient group. Because of differing methodology and other factors, the available studies are difficult to compare directly. Nonetheless, they agree that most patients continue to report seizures long term. Healthcare use outcome appears better, with many patients not accessing medical care for seizures. However, many patients have poor psychiatric and economic outcomes. The reasons for this are poorly understood, but may relate more to underlying psychological processes than to the seizures themselves. A better understanding of the psychological underpinnings of PNES will allow more informative study of outcome and thus of the impact of interventions. However, obtaining good outcome information in PNES patients remains a major challenge and may be difficult in some medical systems.

Long-term outcome of brief augmented psychodynamic interpersonal therapy for psychogenic nonepileptic seizures: Seizure control and health care utilization

Epilepsia ◽

10.1111/j.1528-1167.2010.02656.x ◽

2010 ◽

Vol 51 (7) ◽

pp. 1169-1176 ◽

Cited By ~ 86

Author(s):

Rebecca Mayor ◽

Stephanie Howlett ◽

Richard Grünewald ◽

Markus Reuber

Keyword(s):

Health Care ◽

Health Care Utilization ◽

Seizure Control ◽

Care Utilization ◽

Term Outcome ◽

Interpersonal Therapy ◽

Long Term Outcome ◽

Psychological long‐term outcome in patients with psychogenic nonepileptic seizures

Epilepsia ◽

10.1111/epi.14682 ◽

2019 ◽

Vol 60 (4) ◽

pp. 669-678 ◽

Cited By ~ 5

Author(s):

Katrin Walther ◽

Bastian Volbers ◽

Laura Erdmann ◽

Müjgan Dogan Onugoren ◽

Stephanie Gollwitzer ◽

...

Keyword(s):

Term Outcome ◽

Long Term Outcome ◽

Psychogenic nonepileptic seizures treated with psychotherapy: Long-term outcome on seizures and healthcare utilization

Epilepsy & Behavior ◽

10.1016/j.yebeh.2019.05.007 ◽

2019 ◽

Vol 98 ◽

pp. 195-200 ◽

Cited By ~ 1

Author(s):

Mads Deleuran ◽

Karin Nørgaard ◽

Noémi Becser Andersen ◽

Anne Sabers

Keyword(s):

Healthcare Utilization ◽

Term Outcome ◽

Long Term Outcome ◽

Long-term outcome of psychogenic nonepileptic seizures: The role of induction by suggestion

Epilepsy & Behavior ◽

10.1016/j.yebeh.2014.09.076 ◽

2014 ◽

Vol 41 ◽

pp. 140-143 ◽

Cited By ~ 15

Author(s):

Orsola Gambini ◽

Benedetta Demartini ◽

Valentina Chiesa ◽

Katherine Turner ◽

Valentina Barbieri ◽

...

Keyword(s):

Term Outcome ◽

Long Term Outcome ◽

Faculty Opinions recommendation of Long-term outcome of brief augmented psychodynamic interpersonal therapy for psychogenic nonepileptic seizures: seizure control and health care utilization.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8949956.9509054 ◽

2011 ◽

Author(s):

Roderick Duncan

Keyword(s):

Health Care ◽

Health Care Utilization ◽

Seizure Control ◽

Care Utilization ◽

Term Outcome ◽

Interpersonal Therapy ◽

Long Term Outcome ◽

Long-term follow-up in patients with catastrophic epilepsies

Neurology neuropsychiatry Psychosomatics ◽

10.14412/2074-2711-2019-4-77-81 ◽

2019 ◽

Vol 11 (4) ◽

pp. 77-81

Author(s):

K. V. Firsov ◽

A. S. Kotov

Keyword(s):

Brain Magnetic Resonance Imaging ◽

Term Outcome ◽

Long Term Outcome ◽

Long Term Follow Up ◽

History Of ◽

Nonepileptic Seizures ◽

Active Epilepsy ◽

Catastrophic Epilepsy

Objective: to investigate the features of the course and long-term outcome of catastrophic epilepsies. Patients and methods. A total of 130 patients (62 (47.7%) men and 68 (52.3%) women) aged 21 to 78 years were examined. The follow-up was 1 year to 14 years. The inclusion criteria for the investigation were above 18 years of age; severe epilepsy with daily seizures considered as catastrophic epilepsy. The exclusion criteria were a history of nonepileptic seizures of any etiology, as well as noncompliance. The examination included history data collection; seizure diary analysis; clinical and neurological examination; routine EEG and/or EEG-video monitoring; brain magnetic resonance imaging; and laboratory tests. Results and discussion. The onset of epilepsy immediately with catastrophic seizures was observed in 28 (21.5%) patients; this onset was most frequently seen in 18 of the 28 children. At the same time, catastrophic seizures did not appear immediately, but it took some time for them to occur after the onset of active epilepsy in 102 (78.5%) patients. Moreover, the onset of catastrophic seizures could not be associated with any external influences or errors in 58 (56.9%) of these patients taking the drugs. Transition to catastrophic epilepsy could occur both abruptly in 11 (10.8%) patients and gradually in 91 (89.2%). After treatment correction, 16.8% of patients achieved remission at the time of study completion; the frequency of seizures decreased by 50% or more in 27.1% of cases; the effect was absent in 56.1%. Conclusion. Based on the findings, it can be concluded that in catastrophic epilepsy, the probability exists for spontaneous occurrence and remission of destructive seizures, frequently regardless of the therapy. The onset of the disease and that of catastrophic seizures can be spread in time. The efficiency of treatment remains low in patients with catastrophic epilepsies.