Molecular analysis of endometrial serous carcinoma reveals distinct clinicopathologic and genomic subgroups

2022 ◽  
Author(s):  
Douglas I. Lin ◽  
Alexander Fine ◽  
Natalie A. Danziger ◽  
Richard S.P. Huang ◽  
Douglas A. Mata ◽  
...  
Keyword(s):  
Molecular Analysis ◽  
Serous Carcinoma

scholarly journals Immunohistochemical Biomarkers as a Surrogate of Molecular Analysis in Ovarian Carcinomas: A Review of the Literature

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 199 ◽  
Author(s):  
Giacomo Santandrea ◽  
Simonetta Piana ◽  
Riccardo Valli ◽  
Magda Zanelli ◽  
Elisa Gasparini ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
Molecular Analysis ◽  
Immunohistochemical Analysis ◽  
Cost Effective ◽  
Mucinous Carcinoma ◽  
Serous Carcinoma ◽  
Malignant Neoplasms ◽  
Low Grade ◽  
Ovarian Carcinomas ◽  
Novel Target

The term “ovarian carcinoma” encompasses at least five different malignant neoplasms: high-grade serous carcinoma, low-grade serous carcinoma, endometrioid carcinoma, mucinous carcinoma, and clear cell carcinoma. These five histotypes demonstrated distinctive histological, molecular, and clinical features. The rise of novel target therapies and of a tailored oncological approach has demanded an integrated multidisciplinary approach in the setting of ovarian carcinoma. The need to implement a molecular-based classification in the worldwide diagnostic and therapeutic setting of ovarian cancer demanded a search for easy-to-use and cost-effective molecular-surrogate biomarkers, relying particularly on immunohistochemical analysis. The present review focuses on the role of immunohistochemistry as a surrogate of molecular analysis in the everyday diagnostic approach to ovarian carcinomas.

scholarly journals Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097921
Author(s):  
Vladislav V Makarenko ◽  
Dina Kandil ◽  
Ediz F Cosar ◽  
Lloyd Hutchinson ◽  
Ashraf Khan
Keyword(s):  
Gene Mutation ◽  
Molecular Analysis ◽  
Male Patient ◽  
Rare Case ◽  
Serous Carcinoma ◽  
Low Grade ◽  
Male Patients

Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported, and mostly with the limited immunophenotypical characterization. No molecular analysis of PPSC in males has been previously performed. We here describe another case of PPSC in a male patient. A comprehensive molecular analysis of the tumor revealed SF3B1 gene mutation as a possible driver.

Molecular analysis of neurotransmitter release

1998 ◽  
Vol 33 ◽  
pp. 29-41 ◽  
Author(s):  
Giampietro Schiavo ◽  
Gudrun Stenbeck
Keyword(s):  
Molecular Analysis ◽  
Neurotransmitter Release

Molecular analysis of the lissencephaly gene 1 (LIS-1) in medulloblastomas

1996 ◽  
Vol 22 (3) ◽  
pp. 233-242 ◽  
Author(s):  
A. Koch ◽  
J. Tonn ◽  
J. A. Kraus ◽  
N. Sarensen ◽  
S. Albrecht ◽  
...  
Keyword(s):  
Molecular Analysis

Minimal and dynamic bacterial diversity in grease trap revealed by molecular analysis

2012 ◽  
Vol 43 (1) ◽  
pp. 29-41 ◽  
Author(s):  
Lucas F.S. ◽  
Richard F. ◽  
Adolphe Y. ◽  
Haenn S. ◽  
Moilleron R. ◽  
...  
Keyword(s):  
Bacterial Diversity ◽  
Molecular Analysis

The Individuality of Tumour-Stroma Interaction in Non-Small Cell Lung Cancer: Insights from Funtional and Molecular Analysis

Pneumologie ◽  
2009 ◽  
Vol 63 (S 01) ◽  
Author(s):  
S Gottschling ◽  
M Granzow ◽  
R Kuner ◽  
A Jauch ◽  
E Chang Xu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Molecular Analysis ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Tumour Stroma ◽  
Small Cell Lung
Sign in / Sign up

Export Citation Format

Share Document