Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique

1985 ◽  
Vol 55 ◽  
pp. 303-316 ◽  
Author(s):  
Aldo Tomasi ◽  
Emanuele Albano ◽  
Fiorella Biasi ◽  
Trevor F. Slater ◽  
Vanio Vannini ◽  
...  
Keyword(s):  
Free Radical ◽  
Isolated Hepatocytes ◽  
Spin Trapping ◽  
Radical Intermediates ◽  
Esr Spin Trapping ◽  
Spin Trapping Technique

Free Radicals Generated in Photocatalytic Oxidation of Some Amines and Diamines

1996 ◽  
Vol 1 (2) ◽  
Author(s):  
Ciping Chen ◽  
Daohui Lu ◽  
Guangzhi Xu
Keyword(s):  
Free Radicals ◽  
Free Radical ◽  
Photocatalytic Oxidation ◽  
Spin Trapping ◽  
Experimental Results ◽  
Epr Spectra ◽  
Radical Species ◽  
Radical Intermediates ◽  
Radical Adduct ◽  
Spin Trapping Technique

AbstractFree radical intermediates produced during photocatalytic oxidation of some typical amines and diamines were investigated by a spin trapping technique. The EPR spectra of N-centered radical adduct and Ccentered radical adduct were observed. Experimental results disclose that these radicals are participants in the initial steps of photodegradation of these compounds. A mechanism which is consistent with the observation of these radical species is discussed.

scholarly journals Synthesis of Fluorescent Dansyl Derivatives of Methoxyamine and Diphenylhydrazine as Free Radical Precursors

2020 ◽  
Vol 21 (10) ◽  
pp. 3559
Author(s):  
Bianca Patrascu ◽  
Sorin Mocanu ◽  
Anca Coman ◽  
Augustin M. Madalan ◽  
Codruta Popescu ◽  
...  
Keyword(s):  
Free Radical ◽  
Esr Spectroscopy ◽  
Spin Trapping ◽  
X Ray ◽  
Esr Spin Trapping ◽  
Dansyl Derivatives ◽  
Methoxy Radical ◽  
Derivatives Of ◽  
Fluorescent Derivatives ◽  
Spin Trapping Technique

Starting from dansyl-chloride, in reaction with 1,1-diphenylhydrazine and methoxyamine, two new fluorescent derivatives 1 and 2 were obtained and characterized by NMR, IR, UV-Vis, HR-MS, and fluorescence spectroscopy. The single-crystal X-ray structure was obtained for compound 2. Both compounds generate free radicals by oxidation, as demonstrated by ESR spectroscopy. Compound 1 generates the corresponding hydrazyl-persistent free radical, evidenced directly by ESR spectroscopy, while compound 2 generates in the first instance the methoxyaminyl short-lived free radical, which decomposes rapidly with the formation of the methoxy radical, evidenced by the ESR spin-trapping technique. By oxidation of compounds 1 and 2, their fluorescence is quenched.

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