Fluorescence in situ hybridization (FISH) of endoscopic brush cytology from barrett's esophagus detects genetic changes in high-grade dysplasia and adenocarcinoma not seen in patients without dysplasia

2003 ◽  
Vol 124 (4) ◽  
pp. A71
Author(s):  
Marek Skacel ◽  
Mona Fahmy ◽  
Terry L. Gramlich ◽  
Joel E. Richter ◽  
John R. Goldblum ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
High Grade Dysplasia ◽  
High Grade ◽  
Brush Cytology ◽  
Genetic Changes

Fluorescence in situ hybridization mapping of esophagectomy specimens from patients with Barrett's esophagus with high-grade dysplasia or adenocarcinoma

2012 ◽  
Vol 43 (2) ◽  
pp. 172-179 ◽  
Author(s):  
Shannon M. Brankley ◽  
Emily G. Barr Fritcher ◽  
Thomas C. Smyrk ◽  
Matthew E. Keeney ◽  
Michael B. Campion ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
High Grade Dysplasia ◽  
High Grade ◽  
Hybridization Mapping

scholarly journals Barrett's Esophagus and Adenocarcinoma

1988 ◽  
Vol 2 (2) ◽  
pp. 75-78
Author(s):  
Z.W. Li ◽  
A.B.R. Thomson
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
High Grade Dysplasia ◽  
High Grade ◽  
Brush Cytology ◽  
Biopsy Material ◽  
Adenocarcinoma Of The Esophagus ◽  
Routine Surveillance ◽  
Surveillance Endoscopy

As association between Barrett's esophagus and adenocarcinoma of the esophagus is relatively frequent. Survival with adenocarcinoma is generally poor. Routine surveillance endoscopy is suggested with generous biopsy material and brush cytology to detect either high grade dysplasia or intramucosal carcinoma in patients with Barrett's esophagus. Individual cases of high grade dysplasia should be independently confirmed by another pathologist familiar with dysplasia grading. Esophagectomy should be recommended for those patients with high grade dysplasia whose risk for surgery is outweighed by the possible presence or development of cancer.

scholarly journals Detection of genetic changes in Barrett's adenocarcirioma and Barrett's esophagus by DNA in situ hybridization and immunohistochemistry

Cytometry ◽  
1994 ◽  
Vol 15 (2) ◽  
pp. 176-184 ◽  
Author(s):  
K. K. Krishnadath ◽  
H. W. Tilanus ◽  
J. C. Alers ◽  
A. H. Mulder ◽  
H. van Dekken
Keyword(s):  
In Situ Hybridization ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Genetic Changes
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