Tu1060 Role of CagA-Positive Strains of H. pylori in Acute Myocardial Infarction With ST-Segment Elevation

2014 ◽  
Vol 146 (5) ◽  
pp. S-741
Author(s):  
Francesco Franceschi ◽  
Annalisa Tortora ◽  
Marco Roberto ◽  
Giampaolo Niccoli ◽  
Teresa Antonella Di Rienzo ◽  
...  
2020 ◽  
Vol 24 (4) ◽  
pp. 374-385
Author(s):  
Peyman Namdar ◽  
◽  
Leili Yekefallah ◽  
Fatemeh Jalalian ◽  
◽  
...  

According to the latest guidelines, in ST-segment elevation myocardial infarction (STEMI) cases, the best intervention to restore blood flow in the occluded coronary arteries is angioplasty at a time less than 90 minutes. Delay in timely implementation of reperfusion is one of the key problems in the management of STEMI. In this review study, the aim is to investigate the role of pre-hospital and hospital emergency staff in time management of STEMI. For this purpose, the articles published 1999-2019 with available full texts in ProQuest, SID, Science Direct, Google Scholar and Scopus databases were searched using the keywords: Pre-hospital Emergency, Hospital Emergency, Primary Angioplasty, Time Management, Ischemia, and Acute Myocardial Infarction. A total of 59 articles in Persian and English (from 10 different countries) covering both qualitative and quantitative studies were initially yielded. Those which were not a review paper and their full texts were unavailable were excluded from the review. Faster reperfusion reduces the cardiac necrosis area, resulting in reduced morbidity and mortality. Early ECG recording by the pre-hospital emergency team followed by the activation of the code STEMI by the emergency team can increase the speed of diagnosis, decision making, and transfer of the STEMI patient to receive the best treatment.


2006 ◽  
Vol 98 (3) ◽  
pp. 309-313 ◽  
Author(s):  
Barend L. van der Hoeven ◽  
Su-San Liem ◽  
Pranobe V. Oemrawsingh ◽  
Jouke Dijkstra ◽  
J. Wouter Jukema ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
An Hsu ◽  
Shu-Jen Chen ◽  
Yu-Sun Chang ◽  
Hua-Chien Chen ◽  
Pao-Hsien Chu

Background. Recent studies have revealed the role of microRNAs (miRNAs) in a variety of biological and pathological processes, including acute myocardial infarction (AMI). We hypothesized that ST-segment elevation myocardial infarction (STEMI) may be associated with an alteration of miRNAs and that circulating miRNAs may be used as diagnostic markers for STEMI.Methods. Expression levels of 270 serum miRNAs were analyzed in 8 STEMI patients and 8 matched healthy controls to identify miRNAs differentially expressed in the sera of patients with AMI. The differentially expressed miRNAs were evaluated in a separate cohort of 62 subjects, including 31 STEMI patients and 31 normal controls.Results. The initial profiling study identified 12 upregulated and 13 downregulated serum miRNAs in the AMI samples. A subsequent validation study confirmed that serum miR-486-3p and miR-150-3p were upregulated while miR-126-3p, miR-26a-5p, and miR-191-5p were significantly downregulated in the sera of patients with AMI. Ratios between the level of upregulated and downregulated miRNAs were also significantly different in those with AMI. Receiver operator characteristics curve analysis using the expression ratio of miR-486-3p and miR-191-5p showed an area under the curve of 0.863.Conclusion. Our results suggest that serum miRNAs may be used as potential diagnostic biomarkers for STEMI.


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