Scarlet fever immunization by intracutaneous injection of scarlatinal streptococcus toxin

1938 ◽  
Vol 9 (2) ◽  
pp. 125-135 ◽  
Author(s):  
Richard A. Kern ◽  
Jean Crump ◽  
Rudolf L. Roddy ◽  
Sydney Borow
Author(s):  
E.Y. Chi ◽  
M.L. Su ◽  
Y.T. Tien ◽  
W.R. Henderson

Recent attention has been directed to the interaction of the nerve and immune systems. The neuropeptide substance P, a tachykinnin which is a neurotransmitter in the central and peripheral nervous systems produces tissue swelling, augemntation of intersitial fibrin deposition and leukocyte infiltration after intracutaneous injection. There is a direct correlation reported between the extent of mast cell degranulation at the sites of injection and the tissue swelling or granulocyte infiltration. It has previously been demonstrated that antidromic electrical stimulation of sensory nerves induces degranulation of cutaneous mast cells, cutaneous vasodilation and augmented vascular permeability. Morphological studies have documented a close anatiomical association between mast cells and nonmyelinated nerves, that contain substance P and other neuropeptides. However, the presence of mast cells within nerve fasicles has not been previously examined ultrastructurally. In this study, we examined ultrastructurally the distribution of mast cells in the nerve fiber bundles located in the muscular connective tissue of rat tongues (n=20).


BMJ ◽  
1910 ◽  
Vol 1 (2569) ◽  
pp. 784-784
Author(s):  
J. Fletcher
Keyword(s):  

BMJ ◽  
1937 ◽  
Vol 1 (3989) ◽  
pp. 1280-1280
Author(s):  
A. Penman
Keyword(s):  

BMJ ◽  
1926 ◽  
Vol 2 (3421) ◽  
pp. 225-226
Author(s):  
J. H. Garrett
Keyword(s):  

1952 ◽  
Vol 1 (25) ◽  
pp. 850-852
Author(s):  
W. M. Ket
Keyword(s):  

2020 ◽  
Vol 148 ◽  
Author(s):  
N. J. Saad ◽  
N. Muller ◽  
J. Walter ◽  
L. Murajda

Abstract A cluster of 18 scarlet fever cases and large illness absenteeism (32%, 58/184) in a school prompted concern and further investigation. We conducted telephone interviews with parents to ascertain cases and better comprehend parents' views. We identified 19 cases, of which 13 reported scarlet fever diagnosis by a physician and only seven fulfilled the probable case definition. We concluded that the outbreak was far smaller than suspected and found that communication and reporting could be improved. Accurate information and communication is essential in an outbreak; the school's concern could have been alleviated sooner and response measures better targeted.


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