scholarly journals Inhibition of bile salt transport in brush-border membrane vesicles from rat small intestine by photoaffinity labeling.

1983 ◽  
Vol 258 (6) ◽  
pp. 3618-3622 ◽  
Author(s):  
G Burckhardt ◽  
W Kramer ◽  
G Kurz ◽  
F A Wilson
Keyword(s):  
Small Intestine ◽  
Bile Salt ◽  
Brush Border ◽  
Brush Border Membrane ◽  
Photoaffinity Labeling ◽  
Membrane Vesicles ◽  
Brush Border Membrane Vesicles ◽  
Salt Transport ◽  
Rat Small Intestine ◽  
Bile Salt Transport

scholarly journals Sodium ion-coupled uptake of taurocholate by intestinal brush-border membrane vesicles

1979 ◽  
Vol 178 (2) ◽  
pp. 299-303 ◽  
Author(s):  
R C Beesley ◽  
R G Faust
Keyword(s):  
Bile Salt ◽  
Transport System ◽  
Brush Border ◽  
Brush Border Membrane ◽  
Membrane Vesicles ◽  
Brush Border Membrane Vesicles ◽  
Salt Transport ◽  
Intestinal Brush Border Membrane ◽  
Na Ions ◽  
Bile Salt Transport

The uptake of taurocholate was studied in membrane vesicles isolated from brush borders of hamster jejunum and ileum. When an extra- to intra-vesicular gradient of Na+ ions was present ileal vesicles took up 10 times more taurocholate than did jejunal vesicles. Accumulation of taurocholate by ileal vesicles was transient and was due to transport of this bile salt into an osmotically active intravesicular space rather than simple binding. Uptake of taurocholate was specifically dependent on Na+ ions; NaCl and Na2SO4 were capable of supporting accumulation, whereas KCl, LiCl and mannitol were not. Na+-coupled uptake of taurocholate into ileal vesicles was inhibited by other trihydroxy bile salts, by preloading the vesicles with Na+ and by simultaneous flow of glucose into the vesicles. Similarly, vesicular uptake of glucose was inhibited by simultaneous uptake of taurocholate. These results demonstrated that brush-border membrane vesicles prepared from ileum possess an Na+-coupled co-transport system for taurocholate that is similar to the active bile-salt transport system present in the intact ileum.

scholarly journals Transport of thiamine by brush-border membrane vesicles from rat small intestine.

1988 ◽  
Vol 398 (1) ◽  
pp. 329-339 ◽  
Author(s):  
D Casirola ◽  
G Ferrari ◽  
G Gastaldi ◽  
C Patrini ◽  
G Rindi
Keyword(s):  
Small Intestine ◽  
Brush Border ◽  
Brush Border Membrane ◽  
Membrane Vesicles ◽  
Brush Border Membrane Vesicles ◽  
Rat Small Intestine
Sign in / Sign up

Export Citation Format

Share Document