Conversion of the Alzheimer's beta-amyloid precursor protein (APP) Kunitz domain into a potent human neutrophil elastase inhibitor.

Elastase Inhibitor ◽

Kunitz Domain

SC-39026, a specific human neutrophil elastase inhibitor

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(87)90982-x ◽

1987 ◽

Vol 147 (2) ◽

pp. 666-674 ◽

Cited By ~ 10

Author(s):

Akira Nakao ◽

Richard A. Partis ◽

Geralyn P. Jung ◽

Richard A. Mueller

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

A Novel Oral Neutrophil Elastase Inhibitor (ONO-6818) Inhibits Human Neutrophil Elastase-induced Emphysema in Rats

American Journal of Respiratory and Critical Care Medicine ◽

10.1164/rccm.2103118 ◽

2002 ◽

Vol 166 (4) ◽

pp. 496-500 ◽

Cited By ~ 53

Author(s):

Takashige Kuraki ◽

Masayoshi Ishibashi ◽

Masanori Takayama ◽

Motokimi Shiraishi ◽

Minoru Yoshida

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

Exploring the antibacterial potential of human neutrophil elastase inhibitor Ala-Ala-Pro-Val synthesized using microwave-assisted solid phase

10.3390/ecmc2020-07414 ◽

2020 ◽

Author(s):

Helena P. Felgueiras ◽

Sílvia M. M. A. Pereira Lima ◽

A. Francisca G. Silva ◽

Susana P. G. Costa

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

Solid Phase ◽

Elastase Inhibitor ◽

Microwave Assisted ◽

Antibacterial Potential

In vitro studies of a bradykinin B1/B2 antagonist linked to a human neutrophil elastase inhibitor: a heterodimer for the treatment of inflammatory disorders

Canadian Journal of Physiology and Pharmacology ◽

10.1139/cjpp-75-6-633 ◽

1997 ◽

Vol 75 (6) ◽

pp. 633-638

Author(s):

A.H. Leimer ◽

H.B. Kroona ◽

J.K. Blodgett ◽

E.T. Whalley ◽

S.E. Ross ◽

...

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

In Vitro Studies ◽

Elastase Inhibitor ◽

Inflammatory Disorders

Isodeoxyhelicobasidin, a novel human neutrophil elastase inhibitor from the culture broth of Volvariella bombycina

The Journal of Antibiotics ◽

10.1038/ja.2009.24 ◽

2009 ◽

Vol 62 (6) ◽

pp. 333-334 ◽

Cited By ~ 4

Author(s):

Guang-Hua Xu ◽

Young-Hee Kim ◽

Soo-Jin Choo ◽

In-Ja Ryoo ◽

Chang-Ji Zheng ◽

...

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

Culture Broth ◽

Conversion of .alpha.1-Antichymotrypsin into a Human Neutrophil Elastase Inhibitor: Demonstration of Variants with Different Association Rate Constants, Stoichiometries of Inhibition, and Complex Stabilities

Biochemistry ◽

10.1021/bi00190a016 ◽

1994 ◽

Vol 33 (24) ◽

pp. 7627-7633 ◽

Cited By ~ 35

Author(s):

Harvey Rubin ◽

Michael Plotnick ◽

Z. Wang ◽

Xuzhuo Liu ◽

Norman M. Schechter ◽

...

Keyword(s):

Rate Constants ◽

Neutrophil Elastase ◽

Human Neutrophil ◽

Association Rate ◽

Elastase Inhibitor ◽

Association Rate Constants ◽

Complex Stabilities

Safety and efficacy of the human neutrophil elastase inhibitor BAY 85-8501 for the treatment of non-cystic fibrosis bronchiectasis: A randomized controlled trial

Pulmonary Pharmacology & Therapeutics ◽

10.1016/j.pupt.2019.03.009 ◽

2019 ◽

Vol 56 ◽

pp. 86-93 ◽

Cited By ~ 15

Author(s):

Henrik Watz ◽

Johannes Nagelschmitz ◽

Anne Kirsten ◽

Frauke Pedersen ◽

Dorina van der Mey ◽

...

Keyword(s):

Cystic Fibrosis ◽

Randomized Controlled Trial ◽

Neutrophil Elastase ◽

Human Neutrophil ◽

Controlled Trial ◽

Elastase Inhibitor ◽

Safety And Efficacy ◽

Randomized Controlled

Clitocynoic Acid, a Novel Human Neutrophil Elastase Inhibitor from the Culture Broth of Clitocybe aurantiaca

Journal of Microbiology and Biotechnology ◽

10.4014/jmb.0903.3033 ◽

2009 ◽

Vol 19 ◽

Cited By ~ 3

Author(s):

Young-Hee Kim

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

Culture Broth ◽

Simultaneous determination of human neutrophil elastase inhibitor (ONO-5046) and its metabolite in plasma and urine by direct injection column-switching HPLC

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/0731-7085(94)90017-5 ◽

1994 ◽

Vol 12 (3) ◽

pp. 397-405 ◽

Cited By ~ 3

Author(s):

Tetsuya Shintani ◽

Mayumi Takamoto ◽

Masafumi Sawada ◽

Hideki Aishita ◽

Terumichi Nakagawa

Keyword(s):

Simultaneous Determination ◽

Neutrophil Elastase ◽

Human Neutrophil ◽

Direct Injection ◽

Column Switching ◽

ChemInform Abstract: Pleurone (I), a Novel Human Neutrophil Elastase Inhibitor from the Fruiting Bodies of the Mushroom Pleurotus eryngii var. ferulae.

ChemInform ◽

10.1002/chin.201201191 ◽

2011 ◽

Vol 43 (1) ◽

pp. no-no

Author(s):

Ik-Soo Lee ◽

In-Ja Ryoo ◽

Kyong-Yeal Kwon ◽

Jong Seog Ahn ◽

Ick-Dong Yoo

Keyword(s):

Neutrophil Elastase ◽

Human Neutrophil ◽

Pleurotus Eryngii ◽

Fruiting Bodies ◽