scholarly journals Carbohydrate-binding proteins in bovine kidney have consensus amino acid sequences of annexin family proteins.

1992 ◽  
Vol 267 (29) ◽  
pp. 20536-20539
Author(s):  
K Kojima ◽  
H.K. Ogawa ◽  
N Seno ◽  
K Yamamoto ◽  
T Irimura ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Seizi Someya ◽  
Masanori Kakuta ◽  
Mizuki Morita ◽  
Kazuya Sumikoshi ◽  
Wei Cao ◽  
...  

Carbohydrate-binding proteins are proteins that can interact with sugar chains but do not modify them. They are involved in many physiological functions, and we have developed a method for predicting them from their amino acid sequences. Our method is based on support vector machines (SVMs). We first clarified the definition of carbohydrate-binding proteins and then constructed positive and negative datasets with which the SVMs were trained. By applying the leave-one-out test to these datasets, our method delivered 0.92 of the area under the receiver operating characteristic (ROC) curve. We also examined two amino acid grouping methods that enable effective learning of sequence patterns and evaluated the performance of these methods. When we applied our method in combination with the homology-based prediction method to the annotated human genome database, H-invDB, we found that the true positive rate of prediction was improved.


2003 ◽  
Vol 36 (7) ◽  
pp. 851-860 ◽  
Author(s):  
A. Plá ◽  
E. Alonso ◽  
F. Batista-Viera ◽  
L. Franco Fraguas

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