Genetic reconstruction and characterization of the recombinant transacylase (E2b) component of bovine branched-chain alpha-keto acid dehydrogenase complex. Implication of histidine 391 as an active site residue.

T A Griffin; D T Chuang

doi:10.1016/s0021-9258(19)38282-1

Genetic reconstruction and characterization of the recombinant transacylase (E2b) component of bovine branched-chain alpha-keto acid dehydrogenase complex. Implication of histidine 391 as an active site residue.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)38282-1 ◽

1990 ◽

Vol 265 (22) ◽

pp. 13174-13180

Author(s):

T A Griffin ◽

D T Chuang

Keyword(s):

Active Site ◽

Keto Acid ◽

Active Site Residue ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Characterization of the promoter-regulatory region and structural organization of E1 alpha gene (BCKDHA) of human branched-chain alpha-keto acid dehydrogenase complex.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)53097-0 ◽

1993 ◽

Vol 268 (11) ◽

pp. 8309-8316

Author(s):

J.L. Chuang ◽

R.P. Cox ◽

D.T. Chuang

Keyword(s):

Structural Organization ◽

Regulatory Region ◽

Keto Acid ◽

Acid Dehydrogenase ◽

Alpha Gene ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Purification and characterization of human liver branched-chain α-keto acid dehydrogenase complex

Biochemical Medicine and Metabolic Biology ◽

10.1016/0885-4505(87)90019-3 ◽

1987 ◽

Vol 37 (2) ◽

pp. 133-141 ◽

Cited By ~ 13

Author(s):

K. Ono ◽

M. Hakozaki ◽

H. Nishimaki ◽

H. Kochi

Keyword(s):

Human Liver ◽

Keto Acid ◽

Purification And Characterization ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Site-Directed Mutagenesis and Functional Analysis of the Active-Site Residues of the E2 Component of Bovine Branched-Chain .alpha.-Keto Acid Dehydrogenase Complex

Biochemistry ◽

10.1021/bi00209a020 ◽

1994 ◽

Vol 33 (43) ◽

pp. 12879-12885 ◽

Cited By ~ 11

Author(s):

Menghsiao Meng ◽

David T. Chuang

Keyword(s):

Functional Analysis ◽

Active Site ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Keto Acid ◽

Active Site Residues ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Characterization of the inner transacylase core.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)38793-8 ◽

1985 ◽

Vol 260 (25) ◽

pp. 13779-13786 ◽

Cited By ~ 8

Author(s):

D T Chuang ◽

C W Hu ◽

L S Ku ◽

P J Markovitz ◽

R P Cox

Keyword(s):

Bovine Liver ◽

Subunit Structure ◽

Keto Acid ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Correction: Purification and Characterization of Branched Chain alpha -Keto Acid Dehydrogenase Complex of Bovine Kidney

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.76.2.1008-a ◽

1979 ◽

Vol 76 (2) ◽

pp. 1008-1008

Keyword(s):

Keto Acid ◽

Purification And Characterization ◽

Bovine Kidney ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Purification and characterization of branched chain -keto acid dehydrogenase complex of bovine kidney

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.75.10.4881 ◽

1978 ◽

Vol 75 (10) ◽

pp. 4881-4885 ◽

Cited By ~ 174

Author(s):

F. H. Pettit ◽

S. J. Yeaman ◽

L. J. Reed

Keyword(s):

Keto Acid ◽

Purification And Characterization ◽

Bovine Kidney ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Characterization of rainbow trout branched-chain α-keto acid dehydrogenase complex: inter-domain segments of the E2 component affect the overall activity

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology ◽

10.1016/s1096-4959(02)00061-1 ◽

2002 ◽

Vol 132 (2) ◽

pp. 433-442 ◽

Cited By ~ 1

Author(s):

Masatoshi Hakozaki ◽

Kazuo Ono ◽

Toshiyuki Suzuki ◽

Hiroaki Hata ◽

Tsutomu Mori ◽

...

Keyword(s):

Rainbow Trout ◽

Keto Acid ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)35950-7 ◽

1992 ◽

Vol 267 (33) ◽

pp. 24090-24096 ◽

Cited By ~ 1

Author(s):

K.S. Lau ◽

W.J. Herring ◽

J.L. Chuang ◽

M McKean ◽

D.J. Danner ◽

...

Keyword(s):

Keto Acid ◽

Gene Encoding ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Mapping of the lipoyl-bearing domain by limited proteolysis.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42477-x ◽

1986 ◽

Vol 261 (1) ◽

pp. 343-349 ◽

Cited By ~ 8

Author(s):

C W Hu ◽

T A Griffin ◽

K S Lau ◽

R P Cox ◽

D T Chuang

Keyword(s):

Limited Proteolysis ◽

Bovine Liver ◽

Subunit Structure ◽

Keto Acid ◽

Acid Dehydrogenase ◽

Liver Mapping ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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Cloning and expression in Escherichia coli of mature E1 beta subunit of bovine mitochondrial branched-chain alpha-keto acid dehydrogenase complex. Mapping of the E1 beta-binding region on E2.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)46029-2 ◽

1992 ◽

Vol 267 (3) ◽

pp. 1881-1887

Author(s):

R M Wynn ◽

J L Chuang ◽

J R Davie ◽

C W Fisher ◽

M A Hale ◽

...

Keyword(s):

Escherichia Coli ◽

Beta Subunit ◽

Cloning And Expression ◽

Keto Acid ◽

Binding Region ◽

Expression In Escherichia Coli ◽

Acid Dehydrogenase ◽

Branched Chain ◽

Acid Dehydrogenase Complex ◽

Dehydrogenase Complex

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