Chiral capillary electrophoresis as predictor for separation of drug enantiomers in continuous flow zone electrophoresis

2000 ◽  
Vol 895 (1-2) ◽  
pp. 51-65 ◽  
Author(s):  
Mathias Wind ◽  
Peter Hoffmann ◽  
Horst Wagner ◽  
Wolfgang Thormann
Keyword(s):  
Capillary Electrophoresis ◽  
Continuous Flow ◽  
Flow Zone ◽  
Zone Electrophoresis ◽  
Chiral Capillary Electrophoresis

Synchronized, Continuous-Flow Zone Electrophoresis

2008 ◽  
Vol 80 (16) ◽  
pp. 6228-6234 ◽  
Author(s):  
Dawid R. Zalewski ◽  
Dietrich Kohlheyer ◽  
Stefan Schlautmann ◽  
Han J. G. E. Gardeniers
Keyword(s):  
Continuous Flow ◽  
Flow Zone ◽  
Zone Electrophoresis

Separation of enzymes fromCandida boidinii crude extract by continuous flow zone electrophoresis

1990 ◽  
Vol 11 (11) ◽  
pp. 937-941 ◽  
Author(s):  
Sunil Nath ◽  
Horst Schütte ◽  
Gerhard Weber ◽  
Helmut Hustedt ◽  
Wolf-Dieter Deckwer
Keyword(s):  
Crude Extract ◽  
Continuous Flow ◽  
Flow Zone ◽  
Zone Electrophoresis

Focusing of Proteins in a Horseshoe Microchannel

2008 ◽  
Author(s):  
Jaesool Shim ◽  
Prashanta Dutta ◽  
Cornelius F. Ivory
Keyword(s):  
Capillary Electrophoresis ◽  
Electric Field ◽  
Isoelectric Focusing ◽  
Ph Gradient ◽  
Complex Geometries ◽  
Electrokinetic Phenomena ◽  
Double Peaks ◽  
Zone Electrophoresis ◽  
Carrier Ampholytes ◽  
Ph Range

Ampholyte based isoelectric focusing (IEF) simulation was conducted to study dispersion of proteins in a horseshoe microchannel. Four model proteins (pls = 6.49, 7.1, 7.93 and 8.6) are focused in a 1 cm long horseshoe channel under an electric field of 300 V/cm. The pH gradient is formed in the presence of 25 biprotic carrier ampholytes (ΔpK = 3.0) within a pH range of 6 to 9. The proteins are focused at 380 sec in a nominal electric field of 300 V/cm. Our numerical results show that the band dispersions of a protein are large during the marching stage, but the dispersions are significantly reduced when the double peaks start to merge. This rearrangement of spreading band is very unique compared to linear electrokinetic phenomena (capillary electrophoresis, zone electrophoresis or electroosmosis) and is independent of channel position and channel shape. Hence, one can perform IEF in complex geometries without incorporating hyperturns.

Reproducible chiral capillary electrophoresis of methamphetamine and its related compounds using a chemically modified capillary having diol groups

2009 ◽  
Vol 28 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Yoshiaki Iwamuro ◽  
Reiko Iio-Ishimaru ◽  
Satoshi Chinaka ◽  
Nariaki Takayama ◽  
Shuji Kodama ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Chemically Modified ◽  
Chiral Capillary Electrophoresis ◽  
Related Compounds

Chiral capillary electrophoresis

2020 ◽  
Vol 124 ◽  
pp. 115807 ◽  
Author(s):  
Samuel Bernardo-Bermejo ◽  
Elena Sánchez-López ◽  
María Castro-Puyana ◽  
María Luisa Marina
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Capillary Electrophoresis
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