Followup Study of Renal Function in Children With Reflux Nephropathy After Resolution of Vesicoureteral Reflux

1997 ◽  
Vol 157 (3) ◽  
pp. 975-979 ◽  
Author(s):  
Ryuichiro Konda ◽  
Kiyohide Sakai ◽  
Shozo Ota ◽  
Atsushi Takeda ◽  
Seiichi Orikasa
Keyword(s):  
Renal Function ◽  
Vesicoureteral Reflux ◽  
Reflux Nephropathy

Followup Study of Renal Function in Children With Reflux Nephropathy After Resolution of Vesicoureteral Reflux

1997 ◽  
pp. 975-979 ◽  
Author(s):  
Ryuichiro Konda ◽  
Kiyohide Sakai ◽  
Shozo Ota ◽  
Atsushi Takeda ◽  
Seiichi Orikasa
Keyword(s):  
Renal Function ◽  
Vesicoureteral Reflux ◽  
Reflux Nephropathy

scholarly journals RENAL FUNCTION IN CHILDREN WITH REFLUX NEPHROPATHY FOLLOWED UP MORE THAN 10 YEARS AFTER DISAPPEARANCE OF VESICOURETERAL REFLUX

1996 ◽  
Vol 87 (11) ◽  
pp. 1236-1242
Author(s):  
Shozo Ota ◽  
Ryuichiro Konda ◽  
Kiyohide Sakai ◽  
Satoru Kuji ◽  
Takahito Hatakeyama ◽  
...  
Keyword(s):  
Renal Function ◽  
Vesicoureteral Reflux ◽  
Reflux Nephropathy

scholarly journals Vesicoureteral Reflux Detected with 99mTc-DTPA Renal Scintigraphy during Evaluation of Renal Function

2015 ◽  
Vol 4 (1) ◽  
pp. 135-138
Author(s):  
Nevena Manevska ◽  
Sinisa Stojanoski ◽  
Venjamin Majstorov ◽  
Daniela Pop-Gjorcheva ◽  
Nikolina Zdraveska ◽  
...  
Keyword(s):  
Renal Function ◽  
Vesicoureteral Reflux ◽  
Left Kidney ◽  
Reflux Nephropathy ◽  
Antireflux Procedure ◽  
Renal Growth ◽  
Radionuclide Cystography ◽  
Direct Radionuclide Cystography ◽  
Term Monitoring

BACKGROUND: Radionuclide techniques, as direct radionuclide cystography and 99mTc-DMSA scintigraphy, have been used in evaluation of vesicoureteral reflux (VUR) and reflux nephropathy (RN) in children. Dynamic 99mTc-DTPA scintigraphy is reserved for evaluation of differential renal function and obstruction in children, where hydronephrosis is detected by ultrasonography (US) pre- or postnatally. CASE REPORT: Six year old boy was prenatally diagnosed with bilateral hydronephrosis. Postnatal, severe bilateral VUR was detected by voiding urethrocytography. US and 99mTc-DTPA scintigraphy performed in the first month of life showed small left kidney that participated with 2% in the global renal function. Bilateral cutaneous ureterostomy has been performed in order to obtain good renal drainage and promote optimal renal growth. Twelve months later, classic antireflux procedure was done. Control 99mTc-DTPA scintigraphy, 5 ys after antireflux surgery, revealed persisting radioactivity during the diuretic phase, in the left kidney that indicated antireflux procedure failure with VUR reappearance. CONCLUSION: 99mTc-DTPA scintigraphy is the first method of choice for long-term monitoring of individual kidney function in children with VUR and other congenital urinary tract anomalies. Additionally, it can be used as indirect radionuclide cystography when rising of radioactivity in the kidney region, during the diuretic phase can indicate presence of VUR.

Vesicoureteral reflux nephropathy Evidence for immunologically mediated glomerular injury

Urology ◽  
1973 ◽  
Vol 2 (5) ◽  
pp. 534-538 ◽  
Author(s):  
Stephen W. Zimmerman ◽  
David T. Uehling ◽  
Peter M. Burkholder
Keyword(s):  
Vesicoureteral Reflux ◽  
Reflux Nephropathy ◽  
Glomerular Injury

scholarly journals Renal scintigraphy in infants with antenatally diagnosed renal pelvis dilatation

2008 ◽  
Vol 65 (4) ◽  
pp. 299-302
Author(s):  
Boris Ajdinovic ◽  
Ljiljana Jaukovic ◽  
Amira Peco-Antic ◽  
Sanja Dugonjic
Keyword(s):  
Renal Function ◽  
Vesicoureteral Reflux ◽  
Ureteropelvic Junction Obstruction ◽  
No Reduction ◽  
Renal Scintigraphy ◽  
Newborn Period ◽  
Antenatal Hydronephrosis ◽  
Differential Renal Function ◽  
Renal Pelvis Dilatation

Background/Aim. Ureteropelvic junction obstruction and vesicoureteral reflux are the most frequent entities identified on the basis of antenatal hydronephrosis. The aim of this study was to determine the incidence and pattern of abnormal renal scintigraphy findings in postnatal investigation of children with antenatal hydronephrosis. Methods. Twenty four infants (19 boys and five girls) presented with antenatal hydronephrosis and mild to moderate hydronephrosis on ultrasound in newborn period were referred for renal scintigraphy. Ten patients with vesicoureteral reflux documented on micturating cystoureterography underwent 99mTc-DMSA renal scintigraphy and 14 patients were subjected to 99mTc-DTPA scintigraphy. Results. Anteroposterior pelvic diameter on ultrasound ranged from 11 to 24 mm. Renal DMSA scans identified congenital scars in two boys with bilateral reflux of grade V and unilateral reflux of grade III. Relative kidney uptake (RKU) less than 40% was found in three, and poor kidney function (RKU less than 10%) in two patients. Significant obstruction was shown on DTPA diuretic renal scintigraphy in 6/14 patients. Some slowing in dranaige (T1/2 greater than 10 minutes) with no reduction in differential renal function was identified in three patients. Differential renal function less than 10% was obtained in one case. Conclusion. A high percent of abnormal renal scintigraphy findings was obtained. Renal scintigraphy was useful in determination of underlying cause of antenatally detected hydronephrosis.

scholarly journals MECHANISMS OF NEPHROSCLEROSIS DEVELOPMENT IN CHILDREN WITH VESICOURETERAL REFLUX

2018 ◽  
Vol 17 (3) ◽  
pp. 186-193
Author(s):  
Olga L. Morozova ◽  
Peter F. Litvitskiy ◽  
Dmitri A. Morozov ◽  
Larisa D. Maltseva
Keyword(s):  
Vesicoureteral Reflux ◽  
Renal Fibrosis ◽  
Molecular Mechanisms ◽  
Reflux Nephropathy ◽  
Disease Development ◽  
Disease Course ◽  
Multiple Choice Tests ◽  
Lecture Material ◽  
Choice Tests ◽  
Higher Medical Education

The lecture discusses the issue of reflux nephropathy for specialists of the system of higher medical education: the article provides the definition, characterizes the epidemiology, risk factors for disease development in children with vesicoureteral reflux, causes and molecular mechanisms of renal fibrosis formation and progression in reflux nephropathy, and markers for diagnosing and predicting the disease course. In order to control the retention of the lecture material, the text includes case problems and multiple-choice tests.

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