Epidemiology of Human T-Lymphotropic Virus Type III and the Risk of the Acquired Immunodeficiency Syndrome

1986 ◽  
Vol 136 (2) ◽  
pp. 549-549
Author(s):  
W.A. Blattner ◽  
R.J. Biggar ◽  
S.H. Weiss ◽  
M. Melbye ◽  
J.J. Goedert
Keyword(s):  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

scholarly journals Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS

Blood ◽  
1986 ◽  
Vol 67 (3) ◽  
pp. 831-834 ◽  
Author(s):  
DW Archibald ◽  
L Zon ◽  
JE Groopman ◽  
MF McLane ◽  
M Essex
Keyword(s):  
At Risk ◽  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
Serum Antibodies ◽  
Aids Patients ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Whole Saliva ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Abstract Whole saliva samples collected from available people at risk in Boston for infection with human T-lymphotropic virus type III (HTLV-III/LAV), from late 1984 through early 1985, were analyzed for the presence of antibodies to viral proteins. Fourteen of 20 (70%) acquired immunodeficiency syndrome (AIDS) patients and 14 of 15 (93%) AIDS- related complex (ARC) patients had salivary antibodies that reacted with the virus-encoded glycoproteins gp160 and gp120 of HTLV-III infected cells. All of the AIDS and ARC patients had serum antibodies to the same antigens. Of 20 sex partners of AIDS/ARC patients, nine (45%) showed anti-HTLV-III antibodies, and four of 18 (22%) healthy homosexual males also were positive for such antibodies. Serum and salivary antibody status were the same in these groups. A minority of those patients positive for salivary antibodies to env gene-encoded gp160 and gp120 also had salivary antibodies to gag gene-encoded proteins of 55,000, 24,000, and/or 17,000 daltons. Immunoglobulin A (IgA) class antibodies comprised the majority of the salivary antibody response. The spectrum of HTLV-III proteins detected by the salivary and serum antibodies was similar. The possibility that secretory IgA from the gut-associated lymphoid system may play a role to restrict salivary transmission of HTLV-III should be considered.

scholarly journals ASUHAN KEPERAWATAN PADA Nn. G.B DAN Tn.M.B.A YANG MENGALAMI HIV/AIDS DENGAN MASALAH PERUBAHAN MEMBRAN MUKOSA ORAL DI RUANG MELATI DAN FLAMBOYAN RSUD Mgr. GABRIEL MANEK, SVD ATAMBUA

2020 ◽  
Vol 2 (02) ◽  
pp. 18-32
Author(s):  
Arny Munika Manafe ◽  
Maria Fatimah W. A Fouk ◽  
Melkianus Ratu
Keyword(s):  
Human Immunodeficiency Virus ◽  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

Latar belakang : Virus yang di kenal sebagai Human T Lymphotropic Virus Type III ( HTLV III ) atau sekarang yang lasim di sebut Human Immunodeficiency Virus ( HIV ). HIV dapat berkembang lebih lanjut menjadi Acquired Immunodeficiency Syndrome (AIDS). Acquire Immunodefiency Sydrom (AIDS  adalah kumpulan gejala penyakit akibat menurunnya sistem kekebalan tubuh oleh virus. Tujuan : Mahasiswa mampu memberikan tindakan bagaiamana perawatan pada pasien HIV/AIDS dengan Perubahan Membran Mukosa Oral yang meliputi pengkajian, diagnosa  keperawatan, perencanaan, pelaksanan dan evaluasi. Metode penelitian: Studi kasus yaitu studi yang mengekspolarasikan suatu masalah asuhan keperawatan pada Nn.G.B dan Tn. M.B.A yang mengalami HIV/AIDS dengan perubahan membran mukosa oral. Hasil: Setelah diberikan Asuhan keperawatan pada Nn. G.B dan Tn. M.B.A dengan perubahan membran mukosa oralyang sudah teratasi. Kesimpulan : Berdasarkan pembahasan pada bab IV  terdahulu maka penulis mengambil kesimpulan dan saran pada Nn.G.B dan Tn.M.B.A dengan proses keperawatan yang terdiri dari Pengkajian, Diagnosa keperawatan, Perencanaan, Pelaksanaan dan Evaluasi masalah teratasi.

scholarly journals Antibody seronegative human T-lymphotropic virus type III (HTLV-III)- infected patients with acquired immunodeficiency syndrome or related disorders

Blood ◽  
1985 ◽  
Vol 66 (3) ◽  
pp. 742-744 ◽  
Author(s):  
JE Groopman ◽  
PI Hartzband ◽  
L Shulman ◽  
SZ Salahuddin ◽  
MG Sarngadharan ◽  
...  
Keyword(s):  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
Blood Donation ◽  
Clinical Course ◽  
Accurate Diagnosis ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Acquired Immunodeficiency ◽  
Virus Culture ◽  
Immunodeficiency Syndrome

Abstract The human T-lymphotropic virus type III (HTLV-III) is the primary cause of the acquired immunodeficiency syndrome (AIDS) and related disorders (ARC). Prior studies have reported that nearly all symptomatic patients with AIDS or ARC manifest antibody to HTLV-III. This observation has engendered efforts to screen for HTLV-III, especially prior to blood donation, with assays for antibody to HTLV-III. We report the first two cases, one with AIDS and one with ARC, that are HTLV-III virus positive but antibody negative. Accurate diagnosis of HTLV-III infection in some cases may require direct virus culture or tests for antigen. In addition, lack of HTLV-III antibody may indicate an atypical clinical course of AIDS.

scholarly journals Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS

Blood ◽  
1986 ◽  
Vol 67 (3) ◽  
pp. 831-834
Author(s):  
DW Archibald ◽  
L Zon ◽  
JE Groopman ◽  
MF McLane ◽  
M Essex
Keyword(s):  
At Risk ◽  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
Serum Antibodies ◽  
Aids Patients ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Whole Saliva ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Whole saliva samples collected from available people at risk in Boston for infection with human T-lymphotropic virus type III (HTLV-III/LAV), from late 1984 through early 1985, were analyzed for the presence of antibodies to viral proteins. Fourteen of 20 (70%) acquired immunodeficiency syndrome (AIDS) patients and 14 of 15 (93%) AIDS- related complex (ARC) patients had salivary antibodies that reacted with the virus-encoded glycoproteins gp160 and gp120 of HTLV-III infected cells. All of the AIDS and ARC patients had serum antibodies to the same antigens. Of 20 sex partners of AIDS/ARC patients, nine (45%) showed anti-HTLV-III antibodies, and four of 18 (22%) healthy homosexual males also were positive for such antibodies. Serum and salivary antibody status were the same in these groups. A minority of those patients positive for salivary antibodies to env gene-encoded gp160 and gp120 also had salivary antibodies to gag gene-encoded proteins of 55,000, 24,000, and/or 17,000 daltons. Immunoglobulin A (IgA) class antibodies comprised the majority of the salivary antibody response. The spectrum of HTLV-III proteins detected by the salivary and serum antibodies was similar. The possibility that secretory IgA from the gut-associated lymphoid system may play a role to restrict salivary transmission of HTLV-III should be considered.

scholarly journals Antibody seronegative human T-lymphotropic virus type III (HTLV-III)- infected patients with acquired immunodeficiency syndrome or related disorders

Blood ◽  
1985 ◽  
Vol 66 (3) ◽  
pp. 742-744
Author(s):  
JE Groopman ◽  
PI Hartzband ◽  
L Shulman ◽  
SZ Salahuddin ◽  
MG Sarngadharan ◽  
...  
Keyword(s):  
Virus Type ◽  
Acquired Immunodeficiency Syndrome ◽  
Blood Donation ◽  
Clinical Course ◽  
Accurate Diagnosis ◽  
T Lymphotropic Virus ◽  
Type Iii ◽  
Acquired Immunodeficiency ◽  
Virus Culture ◽  
Immunodeficiency Syndrome

The human T-lymphotropic virus type III (HTLV-III) is the primary cause of the acquired immunodeficiency syndrome (AIDS) and related disorders (ARC). Prior studies have reported that nearly all symptomatic patients with AIDS or ARC manifest antibody to HTLV-III. This observation has engendered efforts to screen for HTLV-III, especially prior to blood donation, with assays for antibody to HTLV-III. We report the first two cases, one with AIDS and one with ARC, that are HTLV-III virus positive but antibody negative. Accurate diagnosis of HTLV-III infection in some cases may require direct virus culture or tests for antigen. In addition, lack of HTLV-III antibody may indicate an atypical clinical course of AIDS.

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