1637: Sildenafil Improves Erectile Function and Urinary Symptoms in Men with Erectile Dysfunction and Concomitant Lower Urinary Tract Symptoms

2006 ◽  
Vol 175 (4S) ◽  
pp. 527-528 ◽  
Author(s):  
Kevin T. McVary ◽  
Joseph Camps ◽  
Gerard D. Henry ◽  
Susan D. Conner ◽  
Li-Jung Tseng ◽  
...  
2017 ◽  
Vol 11 (1) ◽  
pp. 4-8 ◽  
Author(s):  
Cem Yucel ◽  
Mehmet Zeynel Keskin ◽  
Cetin Levent Peskircioglu

Objective: This study aimed to evaluate the effects of transdermal testosterone administration on lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Materials and Method: Sixty-two male patients with Ageing Male Symptom Questionnaire (AMS-Q) scores over 27 and a total serum testosterone level below 350 ng/dl (12.1 nmol/l) who presented to our urology clinic with complaints of LUTS and ED, were enrolled in this study. Uroflowmetry and the International Prostate Symptom Scale were used to evaluate the severity of LUTS. The International Index of Erectile Function was used to detect the severity of ED. In addition, the AMS-Q was used to quantify the severity of hypogonadism. We randomly divided patients into 2 groups. Thirty-one patients in the first group had transdermal testosterone administered at a daily dose of 50 mg (a sachet of 5 g) on the skin for 3 months. In the second group, 31 patients had a placebo administered for 3 months. The scales were recompleted based on interviews and uroflowmetry was repeated during checks of the patients performed in the first and third months. Results: We detected a decrease in AMS-Q scores and an increase in maximum uroflow rate values and the International Index of Erectile Function scores in the first group compared with the placebo group. Although a decrease was detected in post-treatment International Prostate Symptom Scale scores in the first group, it was not regarded as statistically significant. Conclusion: This study revealed that testosterone replacement therapy is effective in improving LUTS and ED symptoms.


2005 ◽  
Vol 2 (3) ◽  
pp. 438-444 ◽  
Author(s):  
Rahman Shiri ◽  
Jukka Häkkinen ◽  
Juha Koskimäki ◽  
Heini Huhtala ◽  
Anssi Auvinen ◽  
...  

2006 ◽  
Vol 97 (4) ◽  
pp. 763-765 ◽  
Author(s):  
SIDNEY GLINA ◽  
ANTONIO W. SANTANA ◽  
FLAVIO AZANK ◽  
LUIZ F. MELLO ◽  
EDSON D. MOREIRA

2014 ◽  
Vol 86 (4) ◽  
pp. 353 ◽  
Author(s):  
Lorenzo Montesi ◽  
Luigi Quaresima ◽  
Marco Tiroli ◽  
Vito Lacetera ◽  
Ubaldo Cantoro ◽  
...  

Objectives: To evaluate the improvement of Lower Urinary Tract Symptoms (LUTS) and Erectile Function (EF) evaluated before and after Open Simple Prostatectomy, focusing on which patients this procedure allows better outcomes in term of sexual activity. Material and methods: 50 men with large size benign prostatic hyperplasia (BHP) greater than 80 gr were prospectively evaluated before and 6 months after Open Simple Prostatectomy (Freyer procedure) between October 2012 to September 2013. Patients had a pre-operative transrectal ultrasound (TRUS) for volume evaluation and filled pre and post operative questionnaires for International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF-5) score. Results: Mean patients age was 71 years (D.S. 3,5), mean prostate volume results 103 ml (D.S. 23,7); regarding LUTS and EF, mean improvement of IPSS score was 15,3 (D.S. 4) and mean increase of IIEF-5 score was 3,4 (D.S.3). This study highlights a correlation between patients’ age and increase of IIEF-5 score; no correlation with prostate size was found. Conclusion: According to the EAU Guidelines 2014, large size BPH (over 80-100 mL) with LUTS refractory to medical management continue to have open prostatectomy as the treatment of choice. In our experience we found not only an reduction of LUTS after the procedure but also an improvement of erectile function; this improvement was related with patient’s age.


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