α-Phosphoryl sulfoxides. XI. Sulfenylation of α-phosphoryl sulfoxides and a general synthesis of optically active ketene dithioacetal mono-S-oxides

Tetrahedron ◽  
1997 ◽  
Vol 53 (8) ◽  
pp. 2959-2972 ◽  
Author(s):  
Marian Mikołajczyk ◽  
Wanda H. Midura ◽  
Blanka Wladislaw ◽  
Francisco C. Biaggio ◽  
Liliana Marzorati ◽  
...  
ChemInform ◽  
2010 ◽  
Vol 28 (27) ◽  
pp. no-no
Author(s):  
M. MIKOLAJCZYK ◽  
W. H. MIDURA ◽  
B. WLADISLAW ◽  
F. C. BIAGGIO ◽  
L. MARZORATI ◽  
...  

2003 ◽  
Vol 2 (2) ◽  
pp. 147-160 ◽  
Author(s):  
Yoshimi Niwano ◽  
Tetsuto Ohmi ◽  
Akira Seo ◽  
Hiroki Kodama ◽  
Hiroyasu Koga ◽  
...  

2020 ◽  
Author(s):  
Roger Machín Rivera ◽  
Yujin Jang ◽  
Christopher M. Poteat ◽  
Vincent Lindsay

The addition of organometallic reagents to ketones constitutes one of the most straightforward synthetic approaches to tertiary alcohols. However, due to the absence of a well-behaved class of cyclopropanone surrogates accessible in enantioenriched form, such a trivial synthetic disconnection has only received very little attention in the literature for the formation of tertiary cyclopropanols. In this work, we report a simple and high-yielding synthesis 1-substituted cyclopropanols via the addition of diverse organometallic reagents to 1- phenylsulfonylcyclopropanols, acting here as in situ precursors of the corresponding cyclopropanones.The transformation is shown to be amenable to sp, sp2 or sp3 -hybridized organometallic C-nucleophiles under mild conditions, and the use of enantioenriched substrates led to highly diastereoselective additions and the formation of optically active cyclopropanols.


ChemInform ◽  
2010 ◽  
Vol 28 (14) ◽  
pp. no-no
Author(s):  
M. MIKOLAJCZYK ◽  
J. A. KRYSIAK ◽  
W. H. MIDURA ◽  
M. W. WIECZOREK ◽  
J. BLASZCZYK

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