Naturally occurring benzofuran: isolation, structure elucidation and total synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3′-methoxy-4′-hydroxyphenyl)-3-benzo[b]furancarbaldehyde, a novel adenosine A1 receptor ligand isolated from salvia miltiorrhiza bunge (danshen)

Zhen Yang; Po Ming Hon; Kuk Ying Chui; Zun Le Xu; Hson Mou Chang; Chi Ming Lee; Yu Xin Cui; Henry N.C. Wong; Chi Duen Poon; Bing M. Fung

doi:10.1016/s0040-4039(00)78908-8

Naturally occurring benzofuran: isolation, structure elucidation and total synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3′-methoxy-4′-hydroxyphenyl)-3-benzo[b]furancarbaldehyde, a novel adenosine A1 receptor ligand isolated from salvia miltiorrhiza bunge (danshen)

Tetrahedron Letters ◽

10.1016/s0040-4039(00)78908-8 ◽

1991 ◽

Vol 32 (18) ◽

pp. 2061-2064 ◽

Cited By ~ 46

Author(s):

Zhen Yang ◽

Po Ming Hon ◽

Kuk Ying Chui ◽

Zun Le Xu ◽

Hson Mou Chang ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Salvia Miltiorrhiza ◽

Adenosine A1 Receptor ◽

Salvia Miltiorrhiza Bunge ◽

Receptor Ligand ◽

Naturally Occurring ◽

Adenosine A1 ◽

A1 Receptor

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ChemInform Abstract: Naturally Occurring Benzofuran: Isolation, Structure Elucidation, and Total Synthesis of 5-(3-Hydroxypropyl)-7-methoxy-2-(3′-methoxy-4′- hydroxyphenyl)-3-benzo(b)furancarbaldehyde, a Novel Adenosine A1 Receptor Ligand Isolated from Sa

ChemInform ◽

10.1002/chin.199206166 ◽

2010 ◽

Vol 23 (6) ◽

pp. no-no ◽

Cited By ~ 1

Author(s):

Z. YANG ◽

P. M. HON ◽

K. Y. CHUI ◽

Z. L. XU ◽

H. M. CHANG ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Adenosine A1 Receptor ◽

Receptor Ligand ◽

Naturally Occurring ◽

Adenosine A1 ◽

A1 Receptor

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First no-carrier-added radioselenation of an adenosine-A1 receptor ligand

Journal of Labelled Compounds and Radiopharmaceuticals ◽

10.1002/jlcr.829 ◽

2004 ◽

Vol 47 (7) ◽

pp. 415-427 ◽

Cited By ~ 6

Author(s):

Till Blum ◽

Johannes Ermert ◽

Walter Wutz ◽

Dirk Bier ◽

Heinz H. Coenen

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Ligand ◽

Adenosine A1 ◽

A1 Receptor ◽

No Carrier Added

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Evaluation of carbon-11 labeled KF15372 and its ethyl and methyl derivatives as a potential CNS adenosine A1 receptor ligand

Nuclear Medicine and Biology ◽

10.1016/s0969-8051(96)00161-8 ◽

1997 ◽

Vol 24 (1) ◽

pp. 53-59 ◽

Cited By ~ 34

Author(s):

Junko Noguchi ◽

Kiichi Ishiwata ◽

Riko Furuta ◽

Jun-ichi Simada ◽

Motohiro Kiyosawa ◽

...

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Ligand ◽

Adenosine A1 ◽

A1 Receptor ◽

Methyl Derivatives

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ChemInform Abstract: Regioselective Introduction of Carbon-3 Substituents to 5-Alkyl-7- methoxy-2-phenylbenzo(b)furans: Synthesis of a Novel Adenosine A1 Receptor Ligand and Its Derivatives.

ChemInform ◽

10.1002/chin.199320175 ◽

2010 ◽

Vol 24 (20) ◽

pp. no-no

Author(s):

Z. YANG ◽

H. B. LIU ◽

C. M. LEE ◽

H. M. CHANG ◽

H. N. C. WONG

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Ligand ◽

Adenosine A1 ◽

A1 Receptor

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Compounds from Danshen. Part 7. Regioselective introduction of carbon-3 substituents to 5-alkyl-7-methoxy-2-phenylbenzo[b]furans: synthesis of a novel adenosine A1 receptor ligand and its derivatives

The Journal of Organic Chemistry ◽

10.1021/jo00052a046 ◽

1992 ◽

Vol 57 (26) ◽

pp. 7248-7257 ◽

Cited By ~ 64

Author(s):

Zhen Yang ◽

Han Biao Liu ◽

Chi Ming Lee ◽

Hson Mou Chang ◽

Henry N. C. Wong

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Ligand ◽

Adenosine A1 ◽

A1 Receptor

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Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen) [Erratum to document cited in CA112(25):232530g]

The Journal of Organic Chemistry ◽

10.1021/jo00003a089 ◽

1991 ◽

Vol 56 (3) ◽

pp. 1346-1346

Author(s):

Hson Mou Chang ◽

Kwok Ping Cheng ◽

Tai Francis Choang ◽

Hak Fun Chow ◽

Kuk Ying Chui ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Salvia Miltiorrhiza ◽

Salvia Miltiorrhiza Bunge

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Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen)

The Journal of Organic Chemistry ◽

10.1021/jo00298a029 ◽

1990 ◽

Vol 55 (11) ◽

pp. 3537-3543 ◽

Cited By ~ 128

Author(s):

Hson Mou Chang ◽

Kwok Ping Cheng ◽

Tai Francis Choang ◽

Hak Fun Chow ◽

Kuk Ying Chui ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Salvia Miltiorrhiza ◽

Salvia Miltiorrhiza Bunge

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Development and Evaluation of a Versatile Receptor-Ligand Binding Assay Using Cell Membrane Preparations Embedded in an Agarose Gel Matrix and Evaluation with the Human Adenosine A1 Receptor

Assay and Drug Development Technologies ◽

10.1089/adt.2020.991 ◽

2020 ◽

Vol 18 (7) ◽

pp. 328-340

Author(s):

Dirk Bier ◽

Annette Schulze ◽

Marcus Holschbach ◽

Bernd Neumaier ◽

Arnd Baumann

Keyword(s):

Cell Membrane ◽

Ligand Binding ◽

Binding Assay ◽

Adenosine A1 Receptor ◽

Agarose Gel ◽

Ligand Binding Assay ◽

Receptor Ligand ◽

Adenosine A1 ◽

A1 Receptor

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Effects of rolofylline, a new adenosine A1 receptor antagonist, on symptoms, renal function and outcomes in patients with acute heart failure. Results of the PROTECT pilot study

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(08)60149-6 ◽

2008 ◽

Vol 7 ◽

pp. 53-54

Author(s):

C OCONNOR ◽

G COTTER ◽

H DITTRICH ◽

B DAVISONWEATHERLEY ◽

M METRA ◽

...

Keyword(s):

Heart Failure ◽

Renal Function ◽

Pilot Study ◽

Receptor Antagonist ◽

Acute Heart Failure ◽

Adenosine A1 Receptor ◽

Adenosine A1 ◽

A1 Receptor

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Faculty Opinions recommendation of Heterologous expression of the adenosine A1 receptor in transgenic mouse retina.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1087425.540465 ◽

2007 ◽

Author(s):

Andreas Engel

Keyword(s):

Heterologous Expression ◽

Transgenic Mouse ◽

Adenosine A1 Receptor ◽

Mouse Retina ◽

Adenosine A1 ◽

A1 Receptor

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