Manganese triacetate oxidative lactonisation of electron-rich stilbenes possessing catechol and resorcinol substitution (resveratrol analogues)

2002 ◽  
Vol 43 (17) ◽  
pp. 3151-3155 ◽  
Author(s):  
N.F. Thomas ◽  
K.C. Lee ◽  
Thomas Paraidathathu ◽  
J.F.F. Weber ◽  
K. Awang
Keyword(s):  
Manganese Triacetate ◽  
Resveratrol Analogues

Resveratrol and Resveratrol Analogues—Structure—Activity Relationship

2010 ◽  
Vol 27 (6) ◽  
pp. 1042-1048 ◽  
Author(s):  
Thomas Szekeres ◽  
Monika Fritzer-Szekeres ◽  
Philipp Saiko ◽  
Walter Jäger
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Resveratrol Analogues

Mn(OAc)3 induced C-4 arylations of quinazoline 3-oxides with arylboronic acids

Synthesis ◽  
2021 ◽  
Author(s):  
Rashinikumar Samandram ◽  
Meliha Çetin Korukçu ◽  
Necdet Coskun
Keyword(s):  
Aromatic Rings ◽  
Arylboronic Acids ◽  
Manganese Triacetate ◽  
High Yields

The use of manganese triacetate as an oxidant component in the C-4 arylations of 2-aryl-quinazoline 3-oxides with arylboronic acids is reported. The new protocol was applied to prepare new 2,4-diarylated quinazoline 3-oxides in good to high yields. The method was shown to tolerate various substituents on both aromatic rings, and no complications as deoxygenation and rearrangement to quinazolin-4(3H)-one was observed.

Transition-Metal-Promoted Oxidative Cyclization To Give 1,2,4-Trisubstituted Carbazole Scaffolds

Synthesis ◽  
2019 ◽  
Vol 51 (24) ◽  
pp. 4625-4634
Author(s):  
Milena Szewczyk ◽  
Małgorzata Ryczkowska ◽  
Sławomir Makowiec
Keyword(s):  
Transition Metal ◽  
Oxidative Cyclization ◽  
Oxidizing Agent ◽  
Reaction Intermediate ◽  
Manganese Triacetate ◽  
Unexpected Reaction ◽  
Fused Ring ◽  
Acid Esters

Herein, we describe the synthesis of a 1,2,4-trisubstituted carbazole core from 5-(1H-indol-3-yl)-3-oxopentanoic acid esters or amides. For oxidative cyclization, we tested two different approaches. First, we used manganese triacetate as a conventional moderate oxidizer to ensure the radical course of the reaction. Second, we examined the use of a more complex oxidizing agent I2/Me(OTf)3. In both cases, formation of a fused-ring carbazole system with a 2-hydroxyl and 1-carboxylic substituent were observed. In connection with the formation of an unexpected reaction intermediate, mechanistic aspects of the process were discussed.

Rapid Synthesis of Triazole-Modified Resveratrol Analogues via Click Chemistry

2006 ◽  
Vol 49 (2) ◽  
pp. 467-470 ◽  
Author(s):  
Francesca Pagliai ◽  
Tracey Pirali ◽  
Erika Del Grosso ◽  
Riccardo Di Brisco ◽  
Gian Cesare Tron ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Rapid Synthesis ◽  
Resveratrol Analogues

scholarly journals Synthesis and Bioactivity of Resveratrol Analogues

2014 ◽  
Vol 26 (7) ◽  
pp. 2092-2098 ◽  
Author(s):  
Junli Ao ◽  
Yuanmou Chen ◽  
Xiaoling Xu ◽  
Xu Zhang ◽  
Yue Yu ◽  
...  
Keyword(s):  
Resveratrol Analogues

Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1

2012 ◽  
Vol 20 (17) ◽  
pp. 5117-5126 ◽  
Author(s):  
Renata Mikstacka ◽  
Agnes M. Rimando ◽  
Zbigniew Dutkiewicz ◽  
Tomasz Stefański ◽  
Stanisław Sobiak
Keyword(s):  
Design Synthesis ◽  
Resveratrol Analogues
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