Nicotinic Receptors in the CNS Their Role in Synaptic Transmission

1989 ◽  
Keyword(s):  
Synaptic Transmission ◽  
Nicotinic Receptors

Presynaptic modulation of ganglionic ACh release by muscarinic and nicotinic receptors

1990 ◽  
Vol 259 (2) ◽  
pp. R288-R293
Author(s):  
Z. Dujic ◽  
D. L. Roerig ◽  
H. K. Schedewie ◽  
J. P. Kampine ◽  
Z. J. Bosnjak
Keyword(s):  
Synaptic Transmission ◽  
Nicotinic Receptors ◽  
Stellate Ganglion ◽  
Feedback Regulation ◽  
Compound Action Potential ◽  
Presynaptic Receptors ◽  
Ach Release ◽  
Ganglionic Transmission ◽  
Muscarinic And Nicotinic Receptors ◽  
Compound Action

The present experiments were undertaken to investigate the effects of atropine and d-tubocurarine on acetylcholine (ACh) release and ganglionic synaptic transmission in the isolated cat stellate ganglion. Ganglionic release of picomole amounts of ACh was measured by radioenzymatic assay, and ganglionic transmission was estimated on the basis of the compound action potential recorded from the postganglionic stellate cardiac nerve. Atropine (5 microM) produced a significant increase in both spontaneous and evoked ACh release from the ganglion while depressing synaptic transmission. d-Tubocurarine (20 microM) also caused a significant, though smaller, increase in spontaneous release of ACh but had little effect on evoked release of ACh. These results suggest that ACh release and synaptic transmission in the cat stellate ganglion are subject to cholinergic feedback regulation, which appears to be mediated predominantly via muscarinic presynaptic receptors.

Nicotine smoking concentrations modulate GABAergic synaptic transmission in murine medial prefrontal cortex by activation of α7* and β2* nicotinic receptors

2020 ◽  
Vol 51 (3) ◽  
pp. 781-792
Author(s):  
Roberto Cuevas‐Olguin ◽  
Eric Esquivel‐Rendon ◽  
Jorge Vargas‐Mireles ◽  
Carlos Barajas‐Lόpez ◽  
Roberto Salgado‐Delgado ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Synaptic Transmission ◽  
Medial Prefrontal Cortex ◽  
Nicotinic Receptors ◽  
Gabaergic Synaptic Transmission

scholarly journals Fast synaptic transmission in the goldfish CNS mediated by multiple nicotinic receptors

2011 ◽  
Vol 589 (3) ◽  
pp. 575-595 ◽  
Author(s):  
Charlotte L. Grove ◽  
Theresa M. Szabo ◽  
J. Michael McIntosh ◽  
Samantha C. Do ◽  
Robert F. Waldeck ◽  
...  
Keyword(s):  
Synaptic Transmission ◽  
Nicotinic Receptors
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