A Prospective, Randomized, Double-blind Comparison of Bupivacaine and Lidocaine for Inferior Alveolar Nerve Blocks

2006 ◽  
Vol 2006 ◽  
pp. 275-276
Author(s):  
W.T. Johnson
Keyword(s):  
Inferior Alveolar Nerve ◽  
Nerve Blocks ◽  
Double Blind ◽  
Blind Comparison

A Prospective, Randomized, Double-Blind Comparison of Bupivacaine and Lidocaine for Inferior Alveolar Nerve Blocks

2005 ◽  
Vol 31 (7) ◽  
pp. 499-503 ◽  
Author(s):  
C FERNANDEZ ◽  
A READER ◽  
M BECK ◽  
J NUSSTEIN
Keyword(s):  
Inferior Alveolar Nerve ◽  
Nerve Blocks ◽  
Double Blind ◽  
Blind Comparison

scholarly journals The Effect of 2 Injection Speeds on Local Anesthetic Discomfort During Inferior Alveolar Nerve Blocks

2015 ◽  
Vol 62 (3) ◽  
pp. 106-109 ◽  
Author(s):  
Marcelo Rodrigo de Souza Melo ◽  
Mark Jon Santana Sabey ◽  
Carla Juliane Lima ◽  
Liane Maciel de Almeida Souza ◽  
Francisco Carlos Groppo
Keyword(s):  
Pain Perception ◽  
Crossover Trial ◽  
Healthy Adult ◽  
Inferior Alveolar Nerve ◽  
Needle Insertion ◽  
Test Results ◽  
Nerve Blocks ◽  
Double Blind ◽  
Significant Difference ◽  
Adult Volunteers

Abstract This randomized double-blind crossover trial investigated the discomfort associated with 2 injection speeds, low (60 seconds) and slow (100 seconds), during inferior alveolar nerve block by using 1.8 mL of 2% lidocaine with 1 : 100,000 epinephrine. Three phases were considered: (a) mucosa perforation, (b) needle insertion, and (c) solution injection. Thirty-two healthy adult volunteers needing bilateral inferior alveolar nerve blocks at least 1 week apart were enrolled in the present study. The anesthetic procedure discomfort was recorded by volunteers on a 10-cm visual analog scale in each phase for both injection speeds. Comparison between the 2 anesthesia speeds in each phase was performed by paired t test. Results showed no statistically significant difference between injection speeds regarding perforation (P = .1016), needle placement (P = .0584), or speed injection (P = .1806). The discomfort in all phases was considered low. We concluded that the 2 injection speeds tested did not affect the volunteers' pain perception during inferior alveolar nerve blocks.

Speed of Injection Influences Efficacy of Inferior Alveolar Nerve Blocks: A Double-Blind Randomized Controlled Trial in Volunteers

2006 ◽  
Vol 32 (10) ◽  
pp. 919-923 ◽  
Author(s):  
Mohammad Dib Kanaa ◽  
John Gerard Meechan ◽  
Ian Porter Corbett ◽  
John Martin Whitworth
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Inferior Alveolar Nerve ◽  
Nerve Blocks ◽  
Double Blind ◽  
Randomized Controlled

Efficacy of Ketorolac Buccal Infiltrations and Inferior Alveolar Nerve Blocks in Patients with Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial

2016 ◽  
Vol 42 (5) ◽  
pp. 691-695 ◽  
Author(s):  
Nahid Mohammadzadeh Akhlaghi ◽  
Behnoush Hormozi ◽  
Paul V. Abbott ◽  
Zohreh Khalilak
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Inferior Alveolar Nerve ◽  
Nerve Blocks ◽  
Double Blind ◽  
Irreversible Pulpitis

scholarly journals A Prospective, Randomized, Double-Blind Study of the Anesthetic Efficacy of Sodium Bicarbonate Buffered 2% Lidocaine With 1 : 100,000 Epinephrine in Inferior Alveolar Nerve Blocks

2010 ◽  
Vol 57 (2) ◽  
pp. 59-66 ◽  
Author(s):  
Michael Whitcomb ◽  
Melissa Drum ◽  
Al Reader ◽  
John Nusstein ◽  
Mike Beck
Keyword(s):  
Sodium Bicarbonate ◽  
Inferior Alveolar Nerve ◽  
Crossover Design ◽  
Blind Study ◽  
Double Blind Study ◽  
Nerve Blocks ◽  
Double Blind ◽  
Blind Manner ◽  
Pulpal Anesthesia

Abstract The authors, using a crossover design, randomly administered, in a double-blind manner, inferior alveolar nerve (IAN) blocks using a buffered 2% lidocaine with 1 : 100,000 epinephrine/sodium bicarbonate formulation and an unbuffered 2% lidocaine with 1 : 100,000 epinephrine formulation at 2 separate appointments spaced at least 1 week apart. An electric pulp tester was used in 4-minute cycles for 60 minutes to test for anesthesia of the first and second molars, premolars, and lateral and central incisors. Anesthesia was considered successful when 2 consecutive 80 readings were obtained within 15 minutes, and the 80 reading was continuously sustained for 60 minutes. For the buffered 2% lidocaine with 1 : 100,000 epinephrine/sodium bicarbonate formulation, successful pulpal anesthesia ranged from 10–71%. For the unbuffered 2% lidocaine with 1 : 100,000 epinephrine formulation, successful pulpal anesthesia ranged from 10–72%. No significant differences between the 2 anesthetic formulations were noted. The buffered lidocaine formulation did not statistically result in faster onset of pulpal anesthesia or less pain during injection than did the unbuffered lidocaine formulation. We concluded that buffering a 2% lidocaine with 1 : 100,000 epinephrine with sodium bicarbonate, as was formulated in the current study, did not statistically increase anesthetic success, provide faster onset, or result in less pain of injection when compared with unbuffered 2% lidocaine with 1 : 100,000 epinephrine for an IAN block.

scholarly journals Comparing the Efficacy of Twin Mix and Lidocaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis

2020 ◽  
Vol 67 (4) ◽  
pp. 207-213
Author(s):  
Mamta Kaushik ◽  
Neha Mehra ◽  
Roshni Sharma ◽  
Kishore Moturi ◽  
Uday Kumar Podugu ◽  
...  
Keyword(s):  
Inferior Alveolar Nerve ◽  
Fisher Exact Test ◽  
Success Rates ◽  
Nerve Blocks ◽  
Double Blind ◽  
Lidocaine Group ◽  
Significance Level ◽  
Mandibular Molars ◽  
Significant Difference ◽  
Irreversible Pulpitis

This randomized, active-controlled, double-blind, prospective clinical trial evaluated the anesthetic efficacy of 2% lidocaine with 1:200,000 epinephrine versus an admixture of 2% lidocaine with 1:200,000 epinephrine and 1 mL of 4 mg dexamethasone (Twin mix) for inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP) of the mandibular molars. Seventy-eight patients with SIP of mandibular molars were randomly allocated to the 2 groups of 39 subjects. All patients were required to have profound lip numbness within 10 minutes of local anesthetic deposition. The efficacy of pulpal anesthesia was confirmed by absence of pain or mild pain (Heft-Parker visual analogue scale ≤54 mm) during access cavity preparation and placement of glide path files. The collected data were subjected to independent t test, chi-square test, and Fisher exact test using SPSS software version 20.0 at a significance level of 0.05. IANB success rates for the lidocaine group and the Twin mix group was 66% and 68% respectively, which was not a statistically significant difference (p > .05). This study demonstrated that the anesthetic efficacy of Twin mix was equivalent to 2% lidocaine for IANBs in teeth with SIP.

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