scholarly journals Comparing the Efficacy of Twin Mix and Lidocaine for Inferior Alveolar Nerve Blocks in Patients With Symptomatic Irreversible Pulpitis

2020 ◽  
Vol 67 (4) ◽  
pp. 207-213
Author(s):  
Mamta Kaushik ◽  
Neha Mehra ◽  
Roshni Sharma ◽  
Kishore Moturi ◽  
Uday Kumar Podugu ◽  
...  
Keyword(s):  
Inferior Alveolar Nerve ◽  
Fisher Exact Test ◽  
Success Rates ◽  
Nerve Blocks ◽  
Double Blind ◽  
Lidocaine Group ◽  
Significance Level ◽  
Mandibular Molars ◽  
Significant Difference ◽  
Irreversible Pulpitis

This randomized, active-controlled, double-blind, prospective clinical trial evaluated the anesthetic efficacy of 2% lidocaine with 1:200,000 epinephrine versus an admixture of 2% lidocaine with 1:200,000 epinephrine and 1 mL of 4 mg dexamethasone (Twin mix) for inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP) of the mandibular molars. Seventy-eight patients with SIP of mandibular molars were randomly allocated to the 2 groups of 39 subjects. All patients were required to have profound lip numbness within 10 minutes of local anesthetic deposition. The efficacy of pulpal anesthesia was confirmed by absence of pain or mild pain (Heft-Parker visual analogue scale ≤54 mm) during access cavity preparation and placement of glide path files. The collected data were subjected to independent t test, chi-square test, and Fisher exact test using SPSS software version 20.0 at a significance level of 0.05. IANB success rates for the lidocaine group and the Twin mix group was 66% and 68% respectively, which was not a statistically significant difference (p > .05). This study demonstrated that the anesthetic efficacy of Twin mix was equivalent to 2% lidocaine for IANBs in teeth with SIP.

scholarly journals Anesthetic efficacy of 4% articaine buccal infiltration in the urgency treatment of mandibular molars with symptomatic irreversible pulpitis: a randomized clinical trial

2021 ◽  
Vol 10 (5) ◽  
pp. e32910514651
Author(s):  
Marcelo Capitanio ◽  
Izabela Volpato Marques Tookuni ◽  
Nair Narumi Orita Pavan ◽  
Isolde Terezinha Santos Previdelli ◽  
Angélica Nascimento dos Santos ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pain Perception ◽  
Inferior Alveolar Nerve ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Mandibular Molars ◽  
Significant Difference ◽  
Buccal Infiltration ◽  
Irreversible Pulpitis

The aim of this study was to evaluate the anesthetic efficacy of the 4% articaine by the buccal infiltration technique (BI) after inferior alveolar nerve block (IANB) with 2% mepivacaine, both with 1:100,000 epinephrine, in the urgency treatment of mandibular molars with symptomatic irreversible pulpitis (SIP). This was a prospective study, with a randomized, blinded, controlled parallel clinical trial experimental design. Thirty patients diagnosed with SIP were randomly assigned, and the control group (G1) received the IANB with 1.8 mL of mepivacaine while the experimental group (G2) also received a supplemental BI with 1.8 mL of articaine. To evaluate the anesthetic efficacy, in addition to lip numbness test, the electric pulp testing (EPT) was used. Additionally, a visual analogue scale verified the presence of pain. Two-way ANOVA and Chi-square tests were applied at a significance level of 5%. There was a reduction in pain perception after the two techniques (p<0.001), with no difference between groups (p=0.479). The anesthetic efficacy was 26.6% for IANB (G1) and 40% for IANB plus BI (G2), without significant difference between the two treatments (p=0.699). The BI with 4% articaine after IANB with 2% mepivacaine, both with 1:100,000 epinephrine, did not significantly increase anesthetic success in patients with SIP.

scholarly journals Effect of Preoperative Pain on Inferior Alveolar Nerve Block

2015 ◽  
Vol 62 (4) ◽  
pp. 135-139 ◽  
Author(s):  
Vivek Aggarwal ◽  
Mamta Singla ◽  
Arunajatesan Subbiya ◽  
Paramasivam Vivekanandhan ◽  
Vikram Sharma ◽  
...  
Keyword(s):  
Nerve Block ◽  
Inferior Alveolar Nerve ◽  
Double Blind Study ◽  
Inferior Alveolar Nerve Block ◽  
Success Rates ◽  
Preoperative Pain ◽  
Double Blind ◽  
Mandibular Molar ◽  
Significant Difference ◽  
Irreversible Pulpitis

The present study tested the hypothesis that the amount and severity of preoperative pain will affect the anesthetic efficacy of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis. One-hundred seventy-seven adult volunteer subjects, actively experiencing pain in a mandibular molar, participated in this prospective double-blind study carried out at 2 different centers. The patients were classified into 3 groups on the basis of severity of preoperative pain: mild, 1–54 mm on the Heft-Parker visual analog scale (HP VAS); moderate, 55–114 mm; and severe, greater than 114 mm. After IANB with 1.8 mL of 2% lidocaine, endodontic access preparation was initiated. Pain during treatment was recorded using the HP VAS. The primary outcome measure was the ability to undertake pulp access and canal instrumentation with no or mild pain. The success rates were statistically analyzed by multiple logistic regression test. There was a significant difference between the mild and severe preoperative pain group (P = .03). There was a positive correlation between the values of preoperative and intraoperative pain (r = .2 and .4 at 2 centers). The amount of preoperative pain can affect the anesthetic success rates of IANB in patients with symptomatic irreversible pulpitis.

scholarly journals The Effect of 2 Injection Speeds on Local Anesthetic Discomfort During Inferior Alveolar Nerve Blocks

2015 ◽  
Vol 62 (3) ◽  
pp. 106-109 ◽  
Author(s):  
Marcelo Rodrigo de Souza Melo ◽  
Mark Jon Santana Sabey ◽  
Carla Juliane Lima ◽  
Liane Maciel de Almeida Souza ◽  
Francisco Carlos Groppo
Keyword(s):  
Pain Perception ◽  
Crossover Trial ◽  
Healthy Adult ◽  
Inferior Alveolar Nerve ◽  
Needle Insertion ◽  
Test Results ◽  
Nerve Blocks ◽  
Double Blind ◽  
Significant Difference ◽  
Adult Volunteers

Abstract This randomized double-blind crossover trial investigated the discomfort associated with 2 injection speeds, low (60 seconds) and slow (100 seconds), during inferior alveolar nerve block by using 1.8 mL of 2% lidocaine with 1 : 100,000 epinephrine. Three phases were considered: (a) mucosa perforation, (b) needle insertion, and (c) solution injection. Thirty-two healthy adult volunteers needing bilateral inferior alveolar nerve blocks at least 1 week apart were enrolled in the present study. The anesthetic procedure discomfort was recorded by volunteers on a 10-cm visual analog scale in each phase for both injection speeds. Comparison between the 2 anesthesia speeds in each phase was performed by paired t test. Results showed no statistically significant difference between injection speeds regarding perforation (P = .1016), needle placement (P = .0584), or speed injection (P = .1806). The discomfort in all phases was considered low. We concluded that the 2 injection speeds tested did not affect the volunteers' pain perception during inferior alveolar nerve blocks.

scholarly journals Anaesthetic Efficacy of 4% Articaine in Comparison with 2% Lidocaine as Intraligamentary Injections after an Ineffective Inferior Alveolar Nerve Block in Mandibular Molars with Irreversible Pulpitis: A Prospective Randomised Triple-Blind Clinical Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Nazanin Zargar ◽  
Elnaz Shooshtari ◽  
Leila Pourmusavi ◽  
Alireza Akbarzadeh Baghban ◽  
Hengameh Ashraaf ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Nerve Block ◽  
Repeated Measures ◽  
Inferior Alveolar Nerve ◽  
Inferior Alveolar Nerve Block ◽  
Success Rates ◽  
Chi Square ◽  
Repeated Measures Anova ◽  
Significant Difference ◽  
Irreversible Pulpitis

The objective of the current study was to compare the anaesthetic efficacy of supplemental intraligamentary (IL) injection of 4% articaine with that of 2% lidocaine in the mandibular first and second molars with irreversible pulpitis after an ineffective inferior alveolar nerve block injection (IANB) using the same anaesthetic in a randomised triple-blind clinical trial. Seventy-six adult patients, who were diagnosed with irreversible pulpitis in the mandibular first or second molars, were divided into 2 groups and received IANB randomly. In patients with lip numbness, anaesthesia was evaluated with the cold and electrical pulp (EPT) tests, and if the reported number on EPT was below 100, supplemental IL injection was administered using the same anaesthetic. The teeth were retested after 5 minutes. The Heft–Parker visual analogue scale was used to evaluate pain after IANB and IL injections. Statistical analysis was performed using repeated measures ANOVA, chi-square, and independent-sample and paired-sample t-tests. The results showed that there was no significant difference in the success rates of supplemental IL and IANB injections between articaine and lidocaine. Furthermore, there was no significant difference in the success rates of supplemental IL injection with lidocaine between the mandibular first and second molars. However, there was a significant difference in the success rates of supplemental IL injection with articaine between the mandibular first and second molars. Moreover, supplemental IL injections indicated no significant difference in the anaesthetic efficacy between articaine and lidocaine; nevertheless, they were more effective in the mandibular second molars, especially with articaine.

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