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Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
The Lancet
◽
10.1016/s0140-6736(08)60453-5
◽
2008
◽
Vol 371
(9617)
◽
pp. 987-997
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Cited By ~ 921
Author(s):
Josef S Smolen
◽
Andre Beaulieu
◽
Andrea Rubbert-Roth
◽
Cesar Ramos-Remus
◽
Josef Rovensky
◽
...
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Randomised Trial
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Inhibition
◽
Interleukin 6 Receptor
Download Full-text
Related Documents
Cited By
References
Faculty Opinions recommendation of Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1108512.564581
◽
2008
◽
Author(s):
Johanne Martel-Pelletier
◽
Jean-Pierre Raynauld
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Randomised Trial
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Inhibition
◽
Interleukin 6 Receptor
Download Full-text
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
Yearbook of Dermatology and Dermatologic Surgery
◽
10.1016/s0093-3619(08)79179-2
◽
2009
◽
Vol 2009
◽
pp. 243-244
Author(s):
B.H. Thiers
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Randomised Trial
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Inhibition
◽
Interleukin 6 Receptor
Download Full-text
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
Yearbook of Medicine
◽
10.1016/s0084-3873(09)79339-3
◽
2009
◽
Vol 2009
◽
pp. 8-12
Author(s):
S.M. Berney
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Randomised Trial
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Inhibition
◽
Interleukin 6 Receptor
Download Full-text
Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double-blind, placebo-controlled, dose-escalation trial
Arthritis & Rheumatism
◽
10.1002/art.10623
◽
2002
◽
Vol 46
(12)
◽
pp. 3143-3150
◽
Cited By ~ 356
Author(s):
E. H. S. Choy
◽
D. A. Isenberg
◽
T. Garrood
◽
S. Farrow
◽
Y. Ioannou
◽
...
Keyword(s):
Rheumatoid Arthritis
◽
Monoclonal Antibody
◽
Dose Escalation
◽
Interleukin 6
◽
Therapeutic Benefit
◽
Double Blind
◽
Double Blind Placebo
◽
Interleukin 6 Receptor
◽
Receptor Monoclonal Antibody
Download Full-text
Anti–interleukin-6 receptor antibody therapy favors adrenal androgen secretion in patients with rheumatoid arthritis: A randomized, double-blind, placebo-controlled study
Arthritis & Rheumatism
◽
10.1002/art.21826
◽
2006
◽
Vol 54
(6)
◽
pp. 1778-1785
◽
Cited By ~ 28
Author(s):
Rainer H. Straub
◽
Peter Härle
◽
Seizo Yamana
◽
Takemasa Matsuda
◽
Kiyoshi Takasugi
◽
...
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Antibody Therapy
◽
Controlled Study
◽
Adrenal Androgen
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Antibody
◽
Interleukin 6 Receptor
◽
Androgen Secretion
Download Full-text
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial
Arthritis & Rheumatism
◽
10.1002/art.20303
◽
2004
◽
Vol 50
(6)
◽
pp. 1761-1769
◽
Cited By ~ 563
Author(s):
Norihiro Nishimoto
◽
Kazuyuki Yoshizaki
◽
Nobuyuki Miyasaka
◽
Kazuhiko Yamamoto
◽
Shinichi Kawai
◽
...
Keyword(s):
Rheumatoid Arthritis
◽
Interleukin 6
◽
Controlled Trial
◽
Double Blind
◽
Double Blind Placebo
◽
Receptor Antibody
◽
Interleukin 6 Receptor
Download Full-text
Double-Blind Randomized Controlled Clinical Trial of the Interleukin-6 Receptor Antagonist, Tocilizumab, in European Patients With Rheumatoid Arthritis Who Had an Incomplete Response to Methotrexate
Yearbook of Medicine
◽
10.1016/s0084-3873(08)70006-3
◽
2007
◽
Vol 2007
◽
pp. 8-10
Author(s):
D.L. Kimpel
Keyword(s):
Rheumatoid Arthritis
◽
Clinical Trial
◽
Receptor Antagonist
◽
Interleukin 6
◽
Controlled Clinical Trial
◽
Randomized Controlled Clinical Trial
◽
Double Blind
◽
Randomized Controlled
◽
Incomplete Response
◽
Interleukin 6 Receptor
Download Full-text
Interleukin-6 receptor inhibition with tocilizumab and attainment of disease remission in rheumatoid arthritis: The role of acute-phase reactants
Arthritis & Rheumatism
◽
10.1002/art.27740
◽
2010
◽
Vol 63
(1)
◽
pp. 43-52
◽
Cited By ~ 91
Author(s):
Josef S. Smolen
◽
Daniel Aletaha
Keyword(s):
Rheumatoid Arthritis
◽
Acute Phase
◽
Interleukin 6
◽
Acute Phase Reactants
◽
Disease Remission
◽
Receptor Inhibition
◽
Interleukin 6 Receptor
Download Full-text
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
Arthritis & Rheumatism
◽
10.1002/art.22033
◽
2006
◽
Vol 54
(9)
◽
pp. 2817-2829
◽
Cited By ~ 520
Author(s):
R. N. Maini
◽
P. C. Taylor
◽
J. Szechinski
◽
K. Pavelka
◽
J. Bröll
◽
...
Keyword(s):
Rheumatoid Arthritis
◽
Clinical Trial
◽
Receptor Antagonist
◽
Interleukin 6
◽
Controlled Clinical Trial
◽
Randomized Controlled Clinical Trial
◽
Double Blind
◽
Randomized Controlled
◽
Incomplete Response
◽
Interleukin 6 Receptor
Download Full-text
A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Tocilizumab, An Interleukin-6 Receptor Antibody, For Residual Symptoms in Schizophrenia
Neuropsychopharmacology
◽
10.1038/npp.2017.258
◽
2017
◽
Vol 43
(6)
◽
pp. 1317-1323
◽
Cited By ~ 29
Author(s):
Ragy R Girgis
◽
Adam Ciarleglio
◽
Tse Choo
◽
Gregory Haynes
◽
Joan M Bathon
◽
...
Keyword(s):
Clinical Trial
◽
Interleukin 6
◽
Controlled Clinical Trial
◽
Double Blind
◽
Residual Symptoms
◽
Double Blind Placebo
◽
Receptor Antibody
◽
Interleukin 6 Receptor
Download Full-text
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