scholarly journals Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

The Lancet ◽  
2019 ◽  
Vol 393 (10174) ◽  
pp. 899-909 ◽  
Author(s):  
Caroline Ovadia ◽  
Paul T Seed ◽  
Alexandros Sklavounos ◽  
Victoria Geenes ◽  
Chiara Di Ilio ◽  
...  
Keyword(s):  
Intrahepatic Cholestasis ◽  
Biochemical Markers ◽  
Individual Patient Data ◽  
Perinatal Outcomes ◽  
Patient Data ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Adverse Perinatal Outcomes ◽  
Meta Analyses ◽  
Cholestasis Of Pregnancy

scholarly journals Predictors of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy

2019 ◽  
Vol 90 (4) ◽  
pp. 217-222 ◽  
Author(s):  
Samettin Çelik ◽  
Canan S. Çalışkan ◽  
Handan Çelik ◽  
Mehmet Güçlü ◽  
Alper Başbuğ
Keyword(s):  
Intrahepatic Cholestasis ◽  
Perinatal Outcomes ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Adverse Perinatal Outcomes ◽  
Cholestasis Of Pregnancy

scholarly journals Intrahepatic cholestasis of pregnancy

2021 ◽  
Vol 16 (S3) ◽  
pp. 50-55
Author(s):  
Ana Maria SCUTELNICU ◽  
◽  
Brînduşa Ana CIMPOCA-RAPTIS ◽  
Anca Marina CIOBANU ◽  
Nicolae GICĂ ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Intrahepatic Cholestasis ◽  
Perinatal Outcomes ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Fetal Asphyxia ◽  
Increased Risk ◽  
Adverse Perinatal Outcomes ◽  
Adverse Pregnancy ◽  
Cholestasis Of Pregnancy ◽  
Meconium Stained Amniotic Fluid

Intrahepatic cholestasis of pregnancy is the most common liver disease during pregnancy. The main features are maternal pruritus, in the absence of a rash, and raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of adverse perinatal outcomes, including preterm birth, meconium-stained amniotic fluid, fetal asphyxia with neonatal unit admission or even stillbirth. The main treatment option is ursodeoxycholic acid. We review the etiology, diagnosis, adverse pregnancy outcomes, focusing especially on management of this intriguing condition.

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