Activated protein C resistance in deep-vein thrombosis

The Lancet ◽  
1994 ◽  
Vol 343 (8896) ◽  
pp. 541-542 ◽  
Author(s):  
C LEGNANI
1995 ◽  
Vol 79 (2) ◽  
pp. 227-229 ◽  
Author(s):  
J. Kambayashi ◽  
H. Fujimura ◽  
T. Kawasaki ◽  
M. Sakon ◽  
M. Monden ◽  
...  

2008 ◽  
Vol 392 (1-2) ◽  
pp. 21-24 ◽  
Author(s):  
Arijit Biswas ◽  
Jyoti Bajaj ◽  
Ravi Ranjan ◽  
Arvind Meena ◽  
Mohd. Suhail Akhter ◽  
...  

1995 ◽  
Vol 1 (4) ◽  
pp. 274-276 ◽  
Author(s):  
Antonio Girolami ◽  
Paolo Simioni ◽  
Sandra Zanardi ◽  
Luigi Scarano ◽  
Bruno Girolami

The prevalence of deep vein thrombosis in female patients with antithrombin III (AT III), protein C, or protein S deficiency who are on oral contraception has been compared with that of patients with activated protein C (APC) resistance. In the latter case the prevalence was lower (36.4%) than in the AT III deficiency group (71.4%) but similar to that seen in the protein C and protein S group (25%).' Furthermore, venous thrombosis occurred with APC resistance much later than with AT III, protein C, or protein S defects. The time lag between onset of oral contraception and thrombosis (~16 cycles) was not statistically different from that seen in a group of women who were known to have no antithrombin III, protein C, or protein S defects. It appears that as far as the interaction with oral contraception is concerned APC resistance is a much less severe condition compared with other clotting inhibitor defects. Key Words: Oral contraceptive—Activated protein C resistance—Deep vein thrombosis.


2005 ◽  
Vol 84 (8) ◽  
pp. 799-801 ◽  
Author(s):  
Ryota Ohashi ◽  
Motoi Sugimura ◽  
Takakazu Kawamura ◽  
Naoaki Tamura ◽  
Naohiro Kanayama

Sign in / Sign up

Export Citation Format

Share Document