Cytologic characterization of two distinct alpha satellite DNA domains on human chromosome 7, using double-labeling hybridizations in fluorescence and electron microscopy on a melanoma cell line

1997 ◽  
Vol 96 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Raouf Fetni ◽  
Claude-Lice Richer ◽  
Bernard Malfoy ◽  
Bernard Dutrillaux ◽  
Nicole Lemieux
Keyword(s):  
Electron Microscopy ◽  
Human Chromosome ◽  
Melanoma Cell Line ◽  
Chromosome 7 ◽  
Alpha Satellite ◽  
Double Labeling ◽  
Alpha Satellite Dna ◽  
Fluorescence And Electron Microscopy ◽  
Human Chromosome 7

Partial characterization of cell-surface protein coded for by human chromosome 7

1978 ◽  
Vol 6 (1) ◽  
pp. 293-300 ◽  
Author(s):  
S. R. Ford ◽  
D. P. Aden ◽  
R. Mausner ◽  
G. Trinchieri ◽  
B. B. Knowles
Keyword(s):  
Cell Surface ◽  
Human Chromosome ◽  
Surface Protein ◽  
Chromosome 7 ◽  
Partial Characterization ◽  
Cell Surface Protein ◽  
Human Chromosome 7

Characterization of polymorphic loci on a telomeric fragment of DNA from the long arm of human chromosome 7

Genomics ◽  
1990 ◽  
Vol 8 (1) ◽  
pp. 168-170 ◽  
Author(s):  
Jeanne Dietz-Band ◽  
Harold Riethman ◽  
Carl E. Hildebrand ◽  
Robert Moyzis
Keyword(s):  
Human Chromosome ◽  
Chromosome 7 ◽  
Polymorphic Loci ◽  
Human Chromosome 7

Synteny mapping of five human chromosome 7 genes on bovine chromosomes 4 and 21

1999 ◽  
Vol 84 (1-2) ◽  
pp. 121-124
Author(s):  
E. Antoniou ◽  
J.E. Womack ◽  
M.D. Grosz
Keyword(s):  
Human Chromosome ◽  
Chromosome 7 ◽  
Human Chromosome 7 ◽  
Synteny Mapping

Report of the First International Workshop on Human Chromosome 7 Mapping 1993

1994 ◽  
Vol 65 (1-2) ◽  
pp. 51-73 ◽  
Author(s):  
Karl-Heinz Grzeschik ◽  
Lap-Chee Tsui ◽  
Eric D. Green
Keyword(s):  
Human Chromosome ◽  
International Workshop ◽  
Chromosome 7 ◽  
Human Chromosome 7

scholarly journals Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement.

1990 ◽  
Vol 10 (12) ◽  
pp. 6374-6380 ◽  
Author(s):  
R Wevrick ◽  
W C Earnshaw ◽  
P N Howard-Peebles ◽  
H F Willard
Keyword(s):  
Human Chromosome ◽  
Satellite Dna ◽  
Centromeric Region ◽  
Chromosome Rearrangement ◽  
Specific Antigen ◽  
Chromosome 17 ◽  
Alpha Satellite ◽  
Protein Antigens ◽  
Alpha Satellite Dna ◽  
Human Chromosome 17

A familial, constitutionally rearranged human chromosome 17 is deleted for much of the DNA in its centromeric region but retains full mitotic centromere activity. Fluorescence in situ hybridization, pulsed-field gel electrophoresis, and Southern blot analysis of the residual centromeric region revealed a approximately 700-kb centromeric array of tandemly repeated alpha satellite DNA that was only approximately 20 to 30% as large as a normal array. This deletion was associated with a reduction in the amount of the centromere-specific antigen CENP-B detected by indirect immunofluorescence. The coincidence of the primary constriction, the small residual array of alpha satellite DNA, and the reduced amount of detectable CENP-B support the hypothesis that CENP-B is associated with alpha satellite DNA. Furthermore, the finding that both the deleted chromosome 17 and its derivative supernumerary fragment retained mitotic function and possess centromeric protein antigens suggests that human centromeres are structurally and functionally repetitive.

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