A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product

Author(s):  
Silvia Pellegrini ◽  
Stefano Censini ◽  
Silvia Guidotti ◽  
Paola Iacopetti ◽  
Mariano Rocchi ◽  
...  
1999 ◽  
Vol 40 (12) ◽  
pp. 2279-2292 ◽  
Author(s):  
Mary V. Gamble ◽  
Enyuan Shang ◽  
Roseann Piantedosi Zott ◽  
James R. Mertz ◽  
Debra J. Wolgemuth ◽  
...  

2022 ◽  
Vol 144 ◽  
pp. 295-304
Author(s):  
Kisana Bhinija ◽  
Pattana Srifah Huehne ◽  
Skorn Mongkolsuk ◽  
Somkid Sitthimonchai ◽  
Jutamaad Satayavivad

2007 ◽  
Vol 54 (1) ◽  
pp. 213-218 ◽  
Author(s):  
Shen Liu ◽  
Chaoqun Huang ◽  
Dawei Li ◽  
Weihua Ren ◽  
Haoxing Zhang ◽  
...  

We report here the cloning and characterization of a novel human short-chain dehydrogenases/reductase gene SCDR9, isolated from a human liver cDNA library, and mapped to 4q22.1 by browsing the UCSC genomic database. SCDR9 containing an ORF with a length of 900 bp, encoding a protein with a signal peptide sequence and an adh_short domain. GFP localization shows SCDR9 protein concentrated in some site of the cytoplasm, but not in the ER. Expression pattern in eighteen tissues revealed that SCDR9 is expressed highly in liver. Soluble recombinant protein was successfully purified from Escherichia coli using pET28A(+) expression vector. Our data provides important information for further study of the function of the SCDR9 gene and its products.


Gene ◽  
2000 ◽  
Vol 251 (2) ◽  
pp. 175-186 ◽  
Author(s):  
Kengo Tomita ◽  
Masahiro Sato ◽  
Kagemasa Kajiwara ◽  
Masafumi Tanaka ◽  
Gen Tamiya ◽  
...  

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