EP-1200 SMOKING AND EPSTEIN-BARR VIRUS IGA ANTIBODIES (A MARKER FOR NASOPHARYNGEAL CARCINOMA) IN SINGAPORE CHINESE

2012 ◽  
Vol 103 ◽  
pp. S462
Author(s):  
J. Friborg ◽  
J.M. Yuan ◽  
W.P. Koh ◽  
R. Wang ◽  
S.H. Chan ◽  
...  
2020 ◽  
Vol 11 (24) ◽  
pp. 7176-7183
Author(s):  
Xia Yu ◽  
Fugui Li ◽  
Weimin Cheng ◽  
Biaohua Wu ◽  
Huiyun Fang ◽  
...  

2019 ◽  
Vol 1 (2) ◽  
pp. 275
Author(s):  
Sukri Rahman ◽  
Heru Kurniawan ◽  
Bestari J Budiman ◽  
Eti Yerizel ◽  
Hafni Bachtiar

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1980 ◽  
Vol 88 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Gregory D. Mathew ◽  
Louis F. Qualtiere ◽  
H. Bryan Neel ◽  
Gary R. Pearson

IgA immunoglobulin fractions containing antibodies to Epstein-Barr virus (EBV)-induced membrane antigens were isolated from the sera of two patients with nasopharyngeal carcinoma (NPC), from one non-NPC patient, and from three persons with sera negative for IgA antibodies. IgA antibodies were not cytotoxic against cells expressing EBV-induced membrane antigens in the antibody-dependent cellular cytotoxicity (ADCC) assay. However, IgA antibodies blocked IgG-mediated ADCC, which indicated that these antibodies could serve as a blocking “factor” in patients with disease and, therefore, were potentially detrimental to the host.


Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.


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