Mother-to-child transmission of a hepatitis C virus variant with an insertional mutation in its hypervariable region

1996 ◽  
Vol 25 (5) ◽  
pp. 608-613 ◽  
Author(s):  
Hideki Aizaki ◽  
Akihiko Saito ◽  
Isao Kusakawa ◽  
Yoshihisa Ashiwara ◽  
Seishi Nagamori ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hypervariable Region ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Virus Variant ◽  
Insertional Mutation ◽  
Mother To Child

scholarly journals Hepatitis C Virus Infection in Children and Pregnant Women: An Updated Review of the Literature on Screening and Treatments

2020 ◽  
Vol 10 (01) ◽  
pp. e121-e127 ◽  
Author(s):  
Rosalia Ragusa ◽  
Liberato Simone Corsaro ◽  
Evelise Frazzetto ◽  
Emanuele Bertino ◽  
Maria Alessandra Bellia ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pregnant Women ◽  
Hcv Infection ◽  
Treatment Programs ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother And Child ◽  
Women And Children ◽  
Mother To Child

Abstract Objective The aim of the paper is to review the current information relating to the diagnosis and treatment of hepatitis C virus (HCV) infection in pregnant women and children, particularly those infected by mother-to-child transmission. Study Design A review of published literature was performed to identify relevant articles published between January 2015 and March 2019 on: HCV infection in pregnant woman, mother-to child-transmission of HCV and HCV infection in pediatrics. The results of the evaluation of the different studies were summarized in two sections describing separately the screening and effective treatments in pregnant women and children. Results The rate of mother-to-child transmission of HCV is approximately 5%. HCV infection is strongly associated with cholestasis and preterm birth. Prenatal diagnosis of hepatitis C virus has a dual benefit for mother and child. Perinatally infected children develop cirrhosis in earlier age than those who acquire HCV as adolescents. Pregnant women with cirrhosis have a higher risk of poor maternal and neonatal outcomes than those without cirrhosis. Conclusion To improve public health, universal screening of pregnant women for HCV infection should be performed. Early identification of women and children with HCV infection is important to enable them to be included in assessment and/or treatment programs.

scholarly journals Update on hepatitis C and implications for pregnancy

2017 ◽  
Vol 10 (4) ◽  
pp. 157-160 ◽  
Author(s):  
Jeffrey J Post
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Breast Feeding ◽  
Mode Of Delivery ◽  
Mother To Child Transmission ◽  
Hepatitis C Virus Infection ◽  
Child Transmission ◽  
Mother To Child ◽  
In Pregnancy

Mother-to-child transmission of hepatitis C virus infection occurs in a significant minority of cases and the diagnosis, treatment and cure of hepatitis C virus infection with direct acting antivirals prior to pregnancy can eliminate this risk in almost all cases. Women with hepatitis C virus infection have increased risks of adverse events in pregnancy and poor perinatal outcomes for their children, although the contribution of hepatitis C virus per se is difficult to determine. Altering the mode of delivery does not reduce mother to child transmission of hepatitis C virus infection, although avoidance of fetal scalp electrodes and other potential high risk procedures is recommended during pregnancy and delivery. Breast feeding has not been demonstrated to be a risk for mother-to-child transmission and avoidance of breast feeding is not recommended, although breast feeding with cracked or bleeding nipples is generally avoided. Safety of the currently available hepatitis C virus antivirals in pregnancy and breastfeeding has not yet been established.

scholarly journals Mother-to-Child Transmission of Hepatitis C Virus (HCV) Among HIV/HCV-Coinfected Women

2012 ◽  
Vol 2 (2) ◽  
pp. 126-135 ◽  
Author(s):  
C. A. Checa Cabot ◽  
S. K. Stoszek ◽  
J. Quarleri ◽  
M. H. Losso ◽  
S. Ivalo ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother To Child

scholarly journals Seronegative Hepatitis C Virus Infection in a Child Infected via Mother-to-Child Transmission

2012 ◽  
Vol 50 (7) ◽  
pp. 2515-2519 ◽  
Author(s):  
A. Larouche ◽  
G. Gaetan ◽  
N. El-Bilali ◽  
M. Quesnel-Vallieres ◽  
S. R. Martin ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Mother To Child Transmission ◽  
Hepatitis C Virus Infection ◽  
Child Transmission ◽  
Mother To Child
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