High-dose radiation therapy for elderly patients with inoperable or unresectable non-small cell lung cancer

Lung Cancer ◽  
2001 ◽  
Vol 32 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Kazushige Hayakawa ◽  
Norio Mitsuhashi ◽  
Susumu Katano ◽  
Yoshihiro Saito ◽  
Yuko Nakayama ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Elderly Patients ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
High Dose ◽  
Small Cell Lung ◽  
Dose Radiation

Non-small-cell lung cancer: should unresectable stage III patients routinely receive high-dose radiation therapy?

1988 ◽  
Vol 6 (3) ◽  
pp. 552-558 ◽  
Author(s):  
D G Payne
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Dose Range ◽  
Small Cell ◽  
High Dose ◽  
Small Cell Lung ◽  
Mediastinal Disease ◽  
Dose Radiation

Non-small-cell lung cancer patients who have unresectable mediastinal disease have a poor prognosis regardless of therapy administered. The various rationales for high-dose radiation therapy with curative intent are reviewed in the context of treatment results reported in the literature. The case for a dose-cure relationship in a clinically practical dose range must be considered unproven. On the other hand, the evidence for dose-response effects suggests that higher dosages could result in improved quality of life. There is a need to further refine reproducible criteria, both anatomic (such as mediastinal involvement) and non-anatomic (such as performance status), to permit more appropriate selection of patients for high-dose treatment. Studies involving less rather than more treatment with appropriate endpoints might be both ethical and appropriate.

scholarly journals Concurrent Daily Cisplatin and High-Dose Radiation Therapy in Patients With Stage III Non-Small Cell Lung Cancer

2018 ◽  
Vol 102 (3) ◽  
pp. 543-551 ◽  
Author(s):  
Edith M.T. Dieleman ◽  
Apollonia L.J. Uitterhoeve ◽  
Meike W. van Hoek ◽  
Rob M. van Os ◽  
Jan Wiersma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Stage Iii ◽  
High Dose ◽  
Small Cell Lung ◽  
Dose Radiation

Outcomes and toxicity following high-dose radiation therapy in 15 fractions for non-small cell lung cancer

2017 ◽  
Vol 7 (6) ◽  
pp. 433-441 ◽  
Author(s):  
Penny Fang ◽  
Cameron W. Swanick ◽  
Todd A. Pezzi ◽  
Zhongxing Liao ◽  
James Welsh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
High Dose ◽  
Small Cell Lung ◽  
Dose Radiation
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