Unilateral sudden hearing loss as a presenting manifestation of chronic myeloid leukemia: case report

2004 ◽  
Vol 130 (2) ◽  
pp. 271-273 ◽  
Author(s):  
Y HSU
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Rubén Martín-Hernández ◽  
Diego Hernando Macías-Rodríguez ◽  
Víctor Martín-Sánchez ◽  
Cristina Cordero-Civantos ◽  
Santiago Santa Cruz-Ruiz ◽  
...  

Acute vestibular deficit as the first sign of leukemia is extremely rare. The literature shows some cases of sudden hearing loss accompanied by instability and associated with hyperviscosity syndrome. We present the case of a patient who presents a harmonic vestibular deficit of the right ear. The complementary studies revealed an abnormally high level of leukocytes. A peripheral blood cytogenetic analysis is performed due to a high suspicion of leukemia, and the results show BCR/ABL fusion gene with a cut point in the M-BCR region, which confirms the diagnosis of chronic myeloid leukemia. In this case we detail the importance of taking hematological disorders into consideration in the differential diagnosis of patients with otoneurological symptoms, and we also review the etiopathogenic mechanisms, symptoms, diagnosis, and therapeutic options for chronic myeloid leukemia with sudden hearing loss and vertigo.


2007 ◽  
Vol 264 (12) ◽  
pp. 1513-1516 ◽  
Author(s):  
Gül Özbilen Acar ◽  
Engin Acıoğlu ◽  
Özgün Enver ◽  
Cem Ar ◽  
Serap Şahin

2017 ◽  
Vol 5 (12) ◽  
pp. 2047-2050
Author(s):  
Yuki Takeyasu ◽  
Atsushi Satake ◽  
Yoshiko Azuma ◽  
Yukie Tsubokura ◽  
Hideaki Yoshimura ◽  
...  

2017 ◽  
Vol 14 (3) ◽  
pp. 3717-3721
Author(s):  
Masahide Yamamoto ◽  
Sayaka Suzuki ◽  
Jun-Ichi Mukae ◽  
Keisuke Tanaka ◽  
Ken Watanabe ◽  
...  

2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Pongprueth Rujirachun ◽  
Apichaya Junyavoraluk ◽  
Weerapat Owattanapanich ◽  
Voraparee Suvannarerg ◽  
Sirinart Sirinvaravong

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