Small Cell Carcinoma of the Larynx and Ectopic Antidiuretic Hormone Secretion

1995 ◽  
Vol 113 (3) ◽  
pp. 301-304 ◽  
Author(s):  
Thomas J. Myers ◽  
Noubar Kessimian
2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098565
Author(s):  
Cai-Fu Zhao ◽  
Su-Fen Zhao ◽  
Ze-Qing Du

Small cell carcinoma of the cervix is a rare malignant tumor in the clinical setting. Clinical manifestations of this tumor are mostly similar to those of normal types of cervical cancer. Small cell carcinoma of the cervix only shows symptoms of neuroendocrine tumors, such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). Most of the hyponatremia caused by SIADH can be managed after removal of the cause. Hyponatremia is a predictor of poor prognosis and can be used as an indicator of partial recurrence. We report a case of small cell carcinoma of the cervix complicated by SIADH. Our patient presented with irregular vaginal bleeding after menopause. After one cycle of chemotherapy, there was trembling of the limbs, and a laboratory examination showed low Na+ and low Cl− levels. After limited water intake, intravenous hypertonic saline, and intermittent diuretic treatment, the patient’s blood Na+ levels returned to normal. After a radical operation, the above-mentioned symptoms disappeared.


2004 ◽  
Vol 128 (11) ◽  
pp. 1279-1282
Author(s):  
Vilkesh R. Jaiswal ◽  
Mai P. Hoang

Abstract Primary laryngeal carcinomas comprise approximately 2% to 5% of all malignancies worldwide. Of these laryngeal carcinomas, approximately 99% are primary squamous cell carcinomas. During the past 30 years, about 160 cases of primary small cell carcinoma of the larynx have been reported. Combined primary squamous and small cell carcinoma of the larynx, the so-called composite tumor of the larynx, is even more rare, with only 13 published cases to date. Although the major risk factors for developing these composite tumors of the larynx are thought to be similar to other more common neoplasms of the larynx, such as squamous cell carcinoma, the treatment and prognosis are different. We report an additional case of combined small cell carcinoma of the larynx and discuss the histogenesis of this unusual neoplasm.


2018 ◽  
Vol 30 ◽  
pp. 46-49 ◽  
Author(s):  
A. Raposo ◽  
A. Marco ◽  
M.E. García-Solano ◽  
M.J. Martínez-Ortiz ◽  
F. García-Purriños ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document