P3-099 Cerebral blood flow in dementia with lewy bodies using statistical parametric mapping analysis of TC-99M HMPAO SPECT: comparison with Alzheimer's disease

2004 ◽  
Vol 25 ◽  
pp. S382-S383
Author(s):  
Kyung-Won Park ◽  
Jae-Woo Kim ◽  
Do-Young Kang ◽  
Tae-You Kim ◽  
Mun-Seong Choi
2015 ◽  
Vol 39 (5-6) ◽  
pp. 360-367 ◽  
Author(s):  
Megumi Haji ◽  
Noriyuki Kimura ◽  
Takuya Hanaoka ◽  
Yasuhiro Aso ◽  
Makoto Takemaru ◽  
...  

Background: This study examined regional cerebral blood flow (rCBF) in Alzheimer's disease (AD) patients with and without subclinical hypothyroidism (SCH). Methods: Eleven AD patients with SCH and 141 AD patients without SCH underwent brain perfusion single photon emission computed tomography (SPECT). The SPECT data were analyzed by statistical parametric mapping (SPM8) and FineSRT. Results: AD patients with SCH showed a significantly decreased rCBF mainly in the temporal lobe and thalamus, whereas those without SCH showed a significantly decreased rCBF in the parietotemporal lobe and cingulate gyrus as well as the frontal lobe. Conclusion: Our findings suggest that SCH may affect cerebral perfusion in regions associated with the memory function.


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