Association of Dopamine Agonist Use With Impulse Control Disorders in Parkinson Disease

2008 ◽  
Vol 2008 ◽  
pp. 75-76
Author(s):  
S. Papapetropoulos
Keyword(s):  
Parkinson Disease ◽  
Dopamine Agonist ◽  
Impulse Control ◽  
Impulse Control Disorders

scholarly journals Association of Dopamine Agonist Use With Impulse Control Disorders in Parkinson Disease

2006 ◽  
Vol 63 (7) ◽  
pp. 969 ◽  
Author(s):  
Daniel Weintraub ◽  
Andrew D. Siderowf ◽  
Marc N. Potenza ◽  
Joseph Goveas ◽  
Knashawn H. Morales ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Dopamine Agonist ◽  
Impulse Control ◽  
Impulse Control Disorders

Impulse control disorders in Chinese Parkinson’s disease patients: The effect of ergot derived dopamine agonist

2011 ◽  
Vol 17 (8) ◽  
pp. 635-637 ◽  
Author(s):  
M. Auyeung ◽  
T.H. Tsoi ◽  
W.K. Tang ◽  
C.M. Cheung ◽  
C.N. Lee ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dopamine Agonist ◽  
Impulse Control ◽  
Impulse Control Disorders

P5-2 Theta subthalamic activity in impulse control disorders in Parkinson disease

2010 ◽  
Vol 121 ◽  
pp. S127
Author(s):  
M. Alegre ◽  
M.C. Rodriguez-Oroz ◽  
J. Lopez-Azcarate ◽  
D. Garcia ◽  
J. Toledo ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Impulse Control ◽  
Impulse Control Disorders

scholarly journals Aripiprazole as a risk factor for impulse control disorders: a systematic review

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S300-S301
Author(s):  
Benjamin Williams ◽  
Benjamin Williams ◽  
Kishen Neelam ◽  
Saumya Singh
Keyword(s):  
Systematic Review ◽  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Dopamine Agonist ◽  
Impulse Control ◽  
Bipolar Affective Disorder ◽  
Impulse Control Disorders ◽  
Risk Of Bias ◽  
Potential Association ◽  
Increased Risk

AimsAripiprazole is an anti-psychotic medication widely used for bipolar affective disorder and depression. It's primary mechanism of action is as a partial dopamine agonist. Aripiprazole's effect on dopamine signalling in the mesolimbic and mesocortical pathways may lead to impulse control disorders, as seen with other dopamine agonist medications. Aripiprazole is often chosen by prescribers because of its favourable side effect profile. There is a need to synthesise the available epidemiological literature on the potential association between aripiprazole use and impulse control disorders. This is needed to inform patients and prescribers of the best available evidence regarding this potential association. Our aim is to conduct a systematic review of the available non case-study evidence on the potential association between aripiprazole and impulse control disorders.MethodDatabases were searched using MEDLINE, PsychINFO, EMBASE, Cochrane Clinical Trials and Web of science. All studies from no earliest date to December 2020 were included; adult patients with a severe and enduring mental illness prescribed antipsychotic medication were included. Cinician diagnosis, structured interview diagnosis, and interviewer or self-completion questionnaires were used to measure prevalence. The study designs included were experimental designs, cohort study, cross-sectional survey and administrative databases. Exclusion criteria being those with traumatic brain injury, psychosis secondary to autoimmune, iatrogenic, chromosomal or metabolic disorder, those with Learning disability or Autistic Spectrum disorders. studies with majority of participants <18yrs. Those who were on other antipsychotic medications in addition to Aripiprazole, were excluded. To ensure quality assurance, we used ROBINS-I tool and GRADE assessment to measure the risk of bias.Result240 records were retrieved, 187 after duplicates were removed. 8 full text articles were assessed for eligibility, of which 4 were included in the qualitative synthesis. 2 studies were analyses of spontaneous adverse drug reaction reporting systems and 2 of health insurance claims databases. All 4 studies found aripiprazole to be associated with greater risk of impulse control disorders. The single study which compared directly with other antipsychotics had a much smaller effect size. Study heterogeneity precluded meta-analysis. All studies were at high risk of bias. The quality of evidence is very low.ConclusionThe available evidence is consistent with the existing warnings regarding increased risk of impulse control disorders in patients prescribed aripiprazole. Clinicians may wish to monitor for this adverse drug reaction. Further research which can account for potential confounders, examines specific impulse control disorders and which is less susceptible to detection and ascertainment biases is required.

Impulse control disorders in Parkinson’ disease: the role of personality and cognitive status

2012 ◽  
Vol 259 (11) ◽  
pp. 2269-2277 ◽  
Author(s):  
Michele Poletti ◽  
Ubaldo Bonuccelli
Keyword(s):  
Parkinson Disease ◽  
Impulse Control ◽  
Cognitive Status ◽  
Impulse Control Disorders

Dopamine Agonist-Induced Impulse Control Disorders

2022 ◽  
pp. 43-53
Author(s):  
Cristina Capatina ◽  
Catalina Poiana ◽  
Maria Fleseriu
Keyword(s):  
Dopamine Agonist ◽  
Impulse Control ◽  
Impulse Control Disorders

Detection of Impulse Control Disorders in Parkinson Disease Patients

2010 ◽  
Vol 16 (6) ◽  
pp. 406-407 ◽  
Author(s):  
Howard D. Weiss ◽  
Elaina S. Hirsch ◽  
James R. Williams ◽  
Leah Swearengin ◽  
Laura Marsh
Keyword(s):  
Parkinson Disease ◽  
Impulse Control ◽  
Impulse Control Disorders

Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management

2009 ◽  
Vol 85 (1009) ◽  
pp. 590-596 ◽  
Author(s):  
K Wu ◽  
M Politis ◽  
P Piccini
Keyword(s):  
Parkinson Disease ◽  
Clinical Features ◽  
Impulse Control ◽  
Impulse Control Disorders
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