Regional central nervous system densities of delta-opioid receptors in alcohol-preferring P, alcohol-nonpreferring NP, and unselected Wistar rats

Alcohol ◽  
2001 ◽  
Vol 25 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Wendy N. Strother ◽  
Eyassu J. Chernet ◽  
Larry Lumeng ◽  
Ting-Kai Li ◽  
William J. McBride
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Receptors ◽  
Wistar Rats ◽  
Delta Opioid Receptors

Quantitative autoradiographic mapping of delta-opioid receptors in the rat central nervous system using [125I][D.Ala2]deltorphin-I

Synapse ◽  
1993 ◽  
Vol 13 (3) ◽  
pp. 231-240 ◽  
Author(s):  
Christine Gouarderes ◽  
Stephane Tellez ◽  
Jean Andr� M. Tafani ◽  
Jean-Marie Zajac
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Opioid Receptors ◽  
Delta Opioid Receptors

Multifaceted Effects of Delta Opioid Receptors and DADLE in Diseases of the Nervous System

2018 ◽  
Vol 15 (2) ◽  
pp. 94-108 ◽  
Author(s):  
Jea-Young Lee ◽  
M. Grant Liska ◽  
Marci Crowley ◽  
Kaya Xu ◽  
Sandra A. Acosta ◽  
...  
Keyword(s):  
Nervous System ◽  
Opioid Receptors ◽  
Delta Opioid Receptors

scholarly journals Standarization of a Protocol of Immunohistochemistry for the Detection of Brain Microglia in Wistar Rats

2017 ◽  
Vol 19 (3) ◽  
pp. 45
Author(s):  
Karol Ramírez Chan DDS, MSc, PhD ◽  
Jaime Jaime Fornaguera-Trías PhD
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immune System ◽  
Wistar Rats ◽  
Secondary Antibody ◽  
Research Activity ◽  
The Central Nervous System ◽  
Near Future ◽  
The Brain ◽  
Microglia Morphology

Objective: Standardize a protocol of immunohistochemistry that has been widely used in C57BL/6J mice to identify microglia of the central nervous system in Wistar rats.  Materials and Methods: This research activity was carried out in two parts. In the first part, a protocol of immunohistochemistry was implemented to identify microglia in the central nervous system of 6 Wistar rats. A primary antibody with reactivity to rat and a specific secondary antibody to the primary were used. Once the protocol was established in rats' brains, an immunological challenge was produced with the intraperitoneal application of lipopolysaccharide in 2 Wistar rats, in order to evidence the changes in microglia morphology.  Results and Discussion: We demonstrate that without making major modifications to the original protocol, it can also be used to identify microglia in adult Wistar rats. In the near future, this immunostaining protocol will be applied to elucidate the bidirectional interaction between the brain and the immune system, under homeostatic conditions and different physiological and pathological stimuli.

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