P.3.d.002 Modulation of neurotrophic mechanisms after chronic treatment with the novel antipsychotic lurasidone in rats

2011 ◽  
Vol 21 ◽  
pp. S507
Author(s):  
A. Luoni ◽  
F. Fumagalli ◽  
F. Calabrese ◽  
M. Ogasa ◽  
G. Racagni ◽  
...  
2005 ◽  
Vol 160 (2) ◽  
pp. 338-343 ◽  
Author(s):  
M.J. Fell ◽  
R. Gibson ◽  
E. McDermott ◽  
G. Sisodia ◽  
K.M. Marshall ◽  
...  

2006 ◽  
Vol 190 (3) ◽  
pp. 373-382 ◽  
Author(s):  
Arlene D. Stark ◽  
Shaun Jordan ◽  
Kelly A. Allers ◽  
Robert L. Bertekap ◽  
Ruoyan Chen ◽  
...  

1993 ◽  
Vol 8 (S2) ◽  
pp. 67s-73s ◽  
Author(s):  
R Fontanges ◽  
J Mimouni ◽  
X de Grieve ◽  
J Picard ◽  
M Pugeat ◽  
...  

SummaryThe effects of the novel antidepressant tianeptine, after acute or chronic administration, were compared in normal and restraint-stressed (30 min or 2 h) Wistar rats. Tianeptine, at the dose of 10 mg/kg, did not exert any effect in non-stressed rats. However, in animals restrained for 30 min, tianeptine reduced the increase of circulating ACTH and β-endorphin levels without modification of corticosterone. Moreover, it antagonized the deficit of vertical exploratory activity in an open field. In rats restrained for 2 hours, a single injection of tianeptine suppressed the stress-induced increase of TAT hepatic activity and moderately attenuated the deficit of activity in the open field. This effect was less marked and not statistically significant after chronic treatment.


2011 ◽  
Vol 81 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Eunice Y. Yuen ◽  
Xiangning Li ◽  
Jing Wei ◽  
Masakuni Horiguchi ◽  
Herbert Y. Meltzer ◽  
...  

1996 ◽  
Vol 6 ◽  
pp. S4-115 ◽  
Author(s):  
P.V. Tran ◽  
M.A. Dellva ◽  
V. Rampey ◽  
G.D. Tollefson ◽  
C.M. Beasley

2004 ◽  
Vol 28 (4) ◽  
pp. 264-268 ◽  
Author(s):  
Jay Hopenwasser ◽  
Ashraf Mozayani ◽  
Terry J. Danielson ◽  
Jeremy Harbin ◽  
Harminder S. Narula ◽  
...  

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