P.5.d.004 Psychiatric comorbidity in elderly patients with vascular cognitive disorder

2015 ◽  
Vol 25 ◽  
pp. S588-S589
Author(s):  
M. Arnaoudova
Keyword(s):  
Elderly Patients ◽  
Psychiatric Comorbidity ◽  
Cognitive Disorder ◽  
Vascular Cognitive Disorder

scholarly journals A Role for New Brain Magnetic Resonance Imaging Modalities in Daily Clinical Practice: Protocol of the Prediction of Cognitive Recovery After Stroke (PROCRAS) Study (Preprint)

2017 ◽  
Author(s):  
Hugo P Aben ◽  
Yael D Reijmer ◽  
Johanna MA Visser-Meily ◽  
Jacoba M Spikman ◽  
Jeroen de Bresser ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Diffusion Tensor ◽  
Brain Connectivity ◽  
Cognitive Disorder ◽  
Practice Setting ◽  
Resonance Imaging ◽  
Cognitive Recovery ◽  
Vascular Cognitive Disorder

BACKGROUND Cognitive impairment is common after acute ischemic stroke, affecting up to 75% of the patients. About half of the patients will show recovery, whereas the others will remain cognitively impaired or deteriorate. It is difficult to predict these different cognitive outcomes. OBJECTIVE The objective of this study is to investigate whether diffusion tensor imaging–based measures of brain connectivity predict cognitive recovery after 1 year, in addition to patient characteristics and stroke severity. A specific premise of the Prediction of Cognitive Recovery After Stroke (PROCRAS) study is that it is conducted in a daily practice setting. METHODS The PROCRAS study is a prospective, mono-center cohort study conducted in a large teaching hospital in the Netherlands. A total of 350 patients suffering from an ischemic stroke who screen positive for cognitive impairment on the Montreal Cognitive Assessment (MoCA<26) in the acute stage will undergo a 3Tesla-Magnetic Resonance Imaging (3T-MRI) with a diffusion-weighted sequence and a neuropsychological assessment. Patients will be classified as being unimpaired, as having a mild vascular cognitive disorder, or as having a major vascular cognitive disorder. One year after stroke, patients will undergo follow-up neuropsychological assessment. The primary endpoint is recovery of cognitive function 1 year after stroke in patients with a confirmed poststroke cognitive disorder. The secondary endpoint is deterioration of cognitive function in the first year after stroke. RESULTS The study is already ongoing for 1.5 years, and thus far, 252 patients have provided written informed consent. Final results are expected in June 2019. CONCLUSIONS The PROCRAS study will show the additional predictive value of diffusion tensor imaging-based measures of brain connectivity for cognitive outcome at 1 year in patients with a poststroke cognitive disorder in a daily clinical practice setting. REGISTERED REPORT IDENTIFIER RR1-10.2196/9431

Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia

2004 ◽  
Vol 226 (1-2) ◽  
pp. 81-87 ◽  
Author(s):  
Gustavo C. Román ◽  
Perminder Sachdev ◽  
Donald R. Royall ◽  
Roger A. Bullock ◽  
Jean-Marc Orgogozo ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Vascular Dementia ◽  
Diagnostic Category ◽  
Vascular Cognitive Impairment ◽  
Cognitive Disorder ◽  
Vascular Cognitive Disorder

scholarly journals Cognitive Impairment in Inpatients with Prurigo Nodularis and Psychiatric Comorbidities

2021 ◽  
Vol 18 (12) ◽  
pp. 6265
Author(s):  
Giuseppe Lanza ◽  
Filomena Irene Ilaria Cosentino ◽  
Raffaele Ferri ◽  
Bartolo Lanuzza ◽  
Maddalena Siragusa ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Psychiatric Comorbidity ◽  
Hospital Admissions ◽  
Combined Treatment ◽  
Retrospective Chart Review ◽  
Cognitive Disorder ◽  
Prurigo Nodularis ◽  
Appropriate Treatment ◽  
Vascular Origin ◽  
Neuroactive Drugs

Background: Prurigo nodularis (PN) is a chronic refractory itchy dermatosis. Although psychiatric comorbidity is known, research in cognitive impairment is lacking. We evaluated the occurrence and types of cognitive impairment in a series of inpatients with PN. Methods: This was a retrospective chart review of all the patients with PN admitted to a referral neurological institute from September 2018 to March 2021. Any neurological and psychiatric disorder, along with neuroactive drugs taken, were concomitantly assessed. Results: A total of 16 patients with PN (median age: 70 years, two males) were selected from a total of 1806 hospital admissions. Most of them had a neurodegenerative cognitive disorder, from mild cognitive impairment (8) to Alzheimer’s disease (1), followed by mixed disorder (degenerative and vascular) in six and vascular dementia in one. Comorbid psychiatric diseases (anxiety and depression) were more common than either individual condition, followed by bipolar disorder, whereas two patients did not show psychiatric manifestations. Most patients were on combined treatment with benzodiazepines and antidepressants. Conclusion: Cognitive impairment can be observed in PN. In addition to screening for psychiatric comorbidity and initiating appropriate treatment or referral, clinicians may also consider the presence of cognitive impairment in PN of both degenerative and vascular origin.

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