Post Exposure Studies with Human Diploid Cell Rabies Vaccine and Purified Chick Embryo Cell Vaccine: Comparative Serological Responses in Man

1989 ◽  
Vol 271 (3) ◽  
pp. 345-350 ◽  
Author(s):  
S.N. Madhusudana ◽  
K.K. Tripathi
Keyword(s):  
Chick Embryo ◽  
Diploid Cell ◽  
Embryo Cell ◽  
Rabies Vaccine ◽  
Cell Vaccine ◽  
Human Diploid Cell ◽  
Post Exposure ◽  
Chick Embryo Cell

Protecting Indian schoolchildren against rabies: Pre-exposure vaccination with purified chick embryo cell vaccine (PCECV) or purified verocell rabies vaccine (PVRV)

2008 ◽  
Vol 4 (5) ◽  
pp. 365-369 ◽  
Author(s):  
Preeti Shanbag ◽  
Nitin Shah ◽  
Madhuri Kulkarni ◽  
Manisha Juvekar ◽  
Shampur N. Madhusudana ◽  
...  
Keyword(s):  
Chick Embryo ◽  
Embryo Cell ◽  
Rabies Vaccine ◽  
Cell Vaccine ◽  
Chick Embryo Cell

scholarly journals Safety and Immunogenicity of purified chick embryo cell rabies vaccine (VaxiRab N) administered intradermally as post exposure prophylaxis

2014 ◽  
Vol 10 (8) ◽  
pp. 2433-2437 ◽  
Author(s):  
Hardanahalli S Ravish ◽  
Veena Vijayashankar ◽  
Shampur N Madhusudana ◽  
Mysore K Sudarshan ◽  
Doddabele HA Narayana ◽  
...  
Keyword(s):  
Chick Embryo ◽  
Embryo Cell ◽  
Rabies Vaccine ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Chick Embryo Cell ◽  
Exposure Prophylaxis

scholarly journals Purified chick embryo cell rabies vaccine: economical multisite intradermal regimen for post-exposure prophylaxis

1987 ◽  
Vol 99 (3) ◽  
pp. 755-765 ◽  
Author(s):  
Pravan Suntharasamai ◽  
M. J. Warrell ◽  
Chaisin Viravan ◽  
Pornthep Chanthavanich ◽  
Sornchai Looareesuwan ◽  
...  
Keyword(s):  
Chick Embryo ◽  
Embryo Cell ◽  
Rabies Vaccine ◽  
Human Rabies ◽  
Post Exposure Prophylaxis ◽  
Protective Efficiency ◽  
Vaccine Regimen ◽  
Post Exposure ◽  
Chick Embryo Cell ◽  
Exposure Prophylaxis

SUMMARYThe standard six-dose intramuscular (i.m.) rabies post-exposure vaccine regimen using a new purified chick embryo cell (PCEC) vaccine was compared with two economical multisite intradermal (i.d.) PCEC regimens, a multisite i.m. PCEC schedule and a subcutaneous regimen using a suckling mouse brain (SMB) rabies vaccine manufactured in Thailand. The neutralizing antibody results for the four-site and eight-site i.d. and the standard i.m. PCEC regimens were similar over 3 months. A three-site i.m. PCEC regimen had no advantage. The SMB vaccine gave the lowest antibody levels. Human rabies immune globulin therapy significantly increased the GMT of all groups on day 7, unlike equine antirabies serum (EARS). Both antisera suppressed antibody responses to PCEC on days 14 and 28. Three generalized reactions probably related to EARS were the only serious side effects. An eight-site i.d. PCEC vaccine regimen proved as immunogenic as the routine i.m. schedule and, if implemented as post-exposure prophylaxis, would be the cheapest widely available tissue culture vaccine regimen. The protective efficiency should now be tested in patients bitten by rabid animals.

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