ACE Inhibitor Blocks Left Ventricular Remodeling in Elderly

2005 ◽  
Vol 38 (21) ◽  
pp. 61
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Ace Inhibitor ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular

scholarly journals Dinamika indeksa massy miokarda levogozheludochka u patsientov s arterial'noygipertoniey II-III stepeni na fone terapiiKo-renitekom i Gizaarom

2010 ◽  
Vol 7 (4) ◽  
pp. 36-38
Author(s):  
A A Kudryavtsev ◽  
A S Ryazanov ◽  
N N Eremenko ◽  
S A Kireev
Keyword(s):  
Thiazide Diuretic ◽  
Ace Inhibitor ◽  
Ventricular Remodeling ◽  
Fixed Combination ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Concentric Hypertrophy ◽  
Number Of Patients ◽  
Lv Mass ◽  
Grade Ii

The regress or left ventricular (LV) hypertrophy is a main end-point of antihypertensive therapy. The aim of the present study was to compare antihypertensive effects of two fixed combination preparations of ACE inhibitor and thiazide diuretic, enalapril 20 mg/hydrochlorthiazide 12,5 mg (Co-renitec) and losartan 50 mg/hydrochlorthiazide 12,5 mg (Hyzaar) on LV mass index (LVMI), types of left ventricular remodeling in patients with grade II-III arterial hypertension. First group was treated with Co-renitec, second group with Hyzaar during 24-weeks period. Results showed that both preparations significantly and to the same degree decrease LVMI. Number of patients with normal LV geometry increases with accompanying decrease in number of patients with concentric hypertrophy and concentric remodeling. The favorable effects were more remarkable in group treated with Hyzaar.

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