Diagnostic significance of FDG-PET and argyrophilic nucleolar organizer regions (AgNORs) in oral squamous cell carcinoma

Oral Oncology ◽  
2004 ◽  
Vol 40 (2) ◽  
pp. 190-198 ◽  
Author(s):  
Mikiko Nakamura ◽  
Kazuo Sano ◽  
Yoshimasa Kitagawa ◽  
Toshiyuki Ogasawara ◽  
Sadahiko Nishizawa ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Fdg Pet ◽  
Nucleolar Organizer ◽  
Nucleolar Organizer Regions ◽  
Diagnostic Significance ◽  
Argyrophilic Nucleolar Organizer Regions

scholarly journals Silver Binding Nucleolar Organizer Regions Dots in Oral Leukoplakia with Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An In Vivo Study

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Fahad Mansoor Samadi ◽  
Bastain Thattil Sebastian ◽  
Anil Singh ◽  
Shaleen Chandra ◽  
Shadab Mohammad ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Nucleolar Organizer ◽  
Oral Leukoplakia ◽  
Epithelial Dysplasia ◽  
Nucleolar Organizer Regions ◽  
Normal Oral Mucosa

Silver binding nucleolar organizer regions (AgNOR) in normal oral mucosa (NOM), oral leukoplakia with epithelial dysplasia (ED), and oral squamous cell carcinoma (OSCC) were studied. The mean AgNOR count per nucleus increased from NOM to ED to OSCC. Tissue showing ED in oral leukoplakia and OSCC cases showed higher counts, wider scatter, and smaller size of AgNOR dots in the nuclei. The study seems to suggest that time method has some potential in distinguishing between NOM and oral leukoplakia with ED and OSCC. Studies of larger numbers are needed to arrive at more substantial conclusions.

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