scholarly journals Study on the nucleolar organizer regions associated protein (Ag-NORs) in oral squamous cell carcinoma and benign lesions.

1992 ◽  
Vol 38 (6) ◽  
pp. 891-895 ◽  
Author(s):  
Yoshikazu HAYATSU ◽  
Kouji MATSUMURA ◽  
Tatsuo Tsuji ◽  
Takashi INOUE ◽  
Hiroshi MORIMOTO ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Fahad Mansoor Samadi ◽  
Bastain Thattil Sebastian ◽  
Anil Singh ◽  
Shaleen Chandra ◽  
Shadab Mohammad ◽  
...  

Silver binding nucleolar organizer regions (AgNOR) in normal oral mucosa (NOM), oral leukoplakia with epithelial dysplasia (ED), and oral squamous cell carcinoma (OSCC) were studied. The mean AgNOR count per nucleus increased from NOM to ED to OSCC. Tissue showing ED in oral leukoplakia and OSCC cases showed higher counts, wider scatter, and smaller size of AgNOR dots in the nuclei. The study seems to suggest that time method has some potential in distinguishing between NOM and oral leukoplakia with ED and OSCC. Studies of larger numbers are needed to arrive at more substantial conclusions.


Cancer ◽  
1994 ◽  
Vol 74 (11) ◽  
pp. 3071-3072
Author(s):  
Anthony E. Bedrick ◽  
Amanda E. Schwint ◽  
Tulia M. Savino ◽  
Hector E. Lanfranchi ◽  
Enrique Marschoff ◽  
...  

Head & Neck ◽  
1997 ◽  
Vol 19 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Xin Xie ◽  
Tom C. Stenersen ◽  
Ole Petter F. Clausen ◽  
Morten Boysen

2015 ◽  
Vol 22 (01) ◽  
pp. 018-026
Author(s):  
Sofia Ali Syed ◽  
Mulazim Hussain Bukhari ◽  
Riaz Ahmed Warraich ◽  
Fauzia Quadir ◽  
Asifa Iqbal ◽  
...  

Background: The aim of this study was to evaluate clinico-pathologicalparameters and the status of argyrophilic nucleolar organizer regions stain in various histologicalgrades of oral squamous cell carcinoma. Materials and Methods: A cross sectional studywas conducted on fifty cases of oral squamous cell carcinoma. The specimen were collectedfrom the department of Oral & Maxillofacial Surgery and processed for hematoxylin and eosinstain and AgNOR stain Pathology Laboratory, King Edward Medical University Lahore. Results:Bidi smoking is associated with oral squamous cell carcinoma. The AgNOR (mAgNOR andpAgNOR) status was significantly low in well differentiated and moderately differentiatedcompared to poorly differentiated oral squamous cell carcinoma (p =0.001). AgNOR size inpoorly differentiated was significantly higher than the AgNOR size in well differentiated oralsquamous cell carcinoma. Similarly the distribution of AgNOR in moderately and poorlydifferentiated oral squamous cell carcinoma was significantly high. The AgNORs index wassignificantly high in poorly differentiated squamous cell carcinoma as compared to welldifferentiated and moderately differentiated squamous cell carcinoma. Conclusions: The useof AgNORs stain is easy, valid and reliable method to assess the histological grading of oralsquamous cell carcinoma and should be used to predict the prognosis of patients.


Sign in / Sign up

Export Citation Format

Share Document