Fast and Effective: Full-Body Examinations Uncover Otherwise Missed Skin Lesions

2005 ◽  
Vol 35 (5) ◽  
pp. 39
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  
Agriculture ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 34
Author(s):  
Mayra Lopez ◽  
Eridia Pacheco ◽  
Janeen Salak-Johnson

Aggression is one of the major welfare concerns among group-housed sows, especially during feeding and regrouping. There are no simple solutions, but any attempt to reduce aggression should be considered. Therefore, the aim was to reduce aggression among group-housed gestating sows by feeding sows different dietary fiber using individual feeding places made from either short- or long-length partitions. Five blocks (n = 36 sows/block) of primiparous and multiparous sows were fed a dietary treatment of either 30% wheat middlings and 15% soybean hulls (MIDD-SY) or 30% distillers dried grains and 30% corn germ meal (DDGS-GM) and housed in pens (9 sows/pen) with individual feeding partitions that were either shoulder (short) or full-body (long) in length. Sow behavior, skin lesions, immune status, and performance were measured. Sow behavior, including aggression and lesion severity scores, were mainly affected by partition length. Aggressive encounters were greater and remained elevated among sows in pens with short partitions until 9 weeks post-grouping but were reduced among sows in pens with long partitions by 3 weeks. During feeding, sows in pens with short ones were more likely to be displaced than were those in pens with long ones. Percentages of time spent lying, standing, eating, and oral–nasal–facial behaviors were also differentially influenced by partition length. Dietary fiber differentially influenced immune status and productivity. For example, sows fed MIDD-SY had higher lymphocyte proliferation and increased neutrophils, while those fed DDGS-GM had deeper backfat and weaned heavier piglets. Overall, the length of the feeding partitions influenced the aggressive encounters, other behaviors, and lesion scores; in turn, the fibrous source differentially influenced several immune measures and sow productivity.


Iproceedings ◽  
10.2196/35393 ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. e35393
Author(s):  
Leah Jones ◽  
Amanda Oakley

Background The suspected skin cancer electronic referral pathway was introduced in 2017. It requires general practitioners to add regional, close-up, and dermoscopic images to a lesion-specific referral template for a teledermatologist to review and advise on management. The virtual lesion clinic is a nurse-led clinic used since 2010 to obtain high-quality images for teledermoscopy assessment. A limitation of both services is the absence of a full-body examination. Objective This study aims to evaluate the number of skin cancers missed during teledermatology assessment. Methods This is a retrospective review of skin lesion referrals to dermatology. Suspected skin cancer referrals made in the latter half of 2020 were compared with referrals to the virtual lesion clinic during a similar time period in 2016. Results The study included 481 patients with 548 lesions in the 2020 suspected skin cancer cohort that were matched for age, sex, and ethnicity to 400 patients with 682 lesions in the 2016 virtual lesion clinic cohort. A total of 41 patients underwent subsequent specialist review in the suspected skin cancer cohort compared to 91 in the virtual lesion clinic cohort. A total of 20% of the suspected skin cancer cohort and 24% of the virtual lesion clinic cohort were found to have at least one additional lesion of concern. The majority of these were keratinocytic skin cancers; there were 2 and 0 additional melanomas or melanoma-in-situ, respectively. The virtual lesion clinic nurses identified additional lesions for imaging in 78 of 400 (20%) patients assessed in the virtual lesion clinic. The teledermatologist determined (author AO) that 73% of these additional lesions were malignant. Of the 548 lesions, 10 (2%) in the suspected skin cancer group were rereferred, none of which had a change in diagnosis. Out of 682 lesions, 16 (2%) in the virtual lesion clinic cohort were rereferred, 6 (1%) of which had a change in diagnosis. Conclusions Patients diagnosed with skin cancer often have multiple lesions of concern. Single-lesion teledermoscopy diagnoses have high concordance with in-person evaluation and histology; however, we have shown that in-person examination may reveal other suspicious lesions. The importance of a full-body skin examination should be emphasized to the referrer. Acknowledgments The Waikato Medical Research Foundation provided financial support for the study. Conflicts of Interest None declared.


2021 ◽  
Author(s):  
Leah Jones ◽  
Amanda Oakley

BACKGROUND The suspected skin cancer electronic referral pathway was introduced in 2017. It requires general practitioners to add regional, close-up, and dermoscopic images to a lesion-specific referral template for a teledermatologist to review and advise on management. The virtual lesion clinic is a nurse-led clinic used since 2010 to obtain high-quality images for teledermoscopy assessment. A limitation of both services is the absence of a full-body examination. OBJECTIVE This study aims to evaluate the number of skin cancers missed during teledermatology assessment. METHODS This is a retrospective review of skin lesion referrals to dermatology. Suspected skin cancer referrals made in the latter half of 2020 were compared with referrals to the virtual lesion clinic during a similar time period in 2016. RESULTS The study included 481 patients with 548 lesions in the 2020 suspected skin cancer cohort that were matched for age, sex, and ethnicity to 400 patients with 682 lesions in the 2016 virtual lesion clinic cohort. A total of 41 patients underwent subsequent specialist review in the suspected skin cancer cohort compared to 91 in the virtual lesion clinic cohort. A total of 20% of the suspected skin cancer cohort and 24% of the virtual lesion clinic cohort were found to have at least one additional lesion of concern. The majority of these were keratinocytic skin cancers; there were 2 and 0 additional melanomas or melanoma-in-situ, respectively. The virtual lesion clinic nurses identified additional lesions for imaging in 78 of 400 (20%) patients assessed in the virtual lesion clinic. The teledermatologist determined (author AO) that 73% of these additional lesions were malignant. Of the 548 lesions, 10 (2%) in the suspected skin cancer group were rereferred, none of which had a change in diagnosis. Out of 682 lesions, 16 (2%) in the virtual lesion clinic cohort were rereferred, 6 (1%) of which had a change in diagnosis. CONCLUSIONS Patients diagnosed with skin cancer often have multiple lesions of concern. Single-lesion teledermoscopy diagnoses have high concordance with in-person evaluation and histology; however, we have shown that in-person examination may reveal other suspicious lesions. The importance of a full-body skin examination should be emphasized to the referrer.


Author(s):  
W.T. Collins ◽  
Charles C. Capen ◽  
Louis Kasza

The widespread contamination of the environment with PCB, a compound used extensively by industry in hydraulic and heat transfer fluids as well as plasticizers and solvents in adhesives and sealants, has resulted in detectable tissue levels in a large portion of the human population, domestic animals, and wildlife. Intoxication with PCB produces severe hepatic necrosis, degeneration of lymphoid tissues and kidney, skin lesions, decreased reproductive performance, reduced feed efficiency, and decreased weight gain. PCB also has been reported to reduce the binding of thyroid hormone to serum proteins and enhance the peripheral metabolism of thyroxine with increased excretion of thyroxine-glucuronide in the bile (Bastomsky, Endocrinology 95: 1150-1155, 1974).The objectives of this investigation were (1) to investigate the histopathologic, histochemical, and ultrastructural changes in thyroid FC produced by the acute (4 week) and chronic (12 week) administration of low (50 ppm) and high (500 ppm) doses of PCB to rats, (2) to correlate these alterations to changes in serum immunoreactive thyroxine concentration, and (3) to investigate the persistence of the effects of PCB on the thyroid gland.


1993 ◽  
Vol 26 (2) ◽  
pp. 215-230
Author(s):  
Gerry F. Funk ◽  
Henry T. Hoffman ◽  
Keith D. Carter
Keyword(s):  

2005 ◽  
Vol 36 (3) ◽  
pp. 44
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  

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