733 THE EFFECT OF NICOTINIC ACID/LAROPIPRANT ON LIPIDS, FASTING PLASMA GLUCOSE, GLYCOSYLATED HEMOGLOBIN AND URIC ACID IN PATIENTS WITH MIXED DYSLIPIDEMIA

2011 ◽  
Vol 12 (1) ◽  
pp. 154
Author(s):  
A. Kei ◽  
E. Liberopoulos ◽  
E. Moutzouri ◽  
C. Rizos ◽  
M. Elisaf
Keyword(s):  
Uric Acid ◽  
Nicotinic Acid ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glycosylated Hemoglobin ◽  
Fasting Plasma ◽  
Mixed Dyslipidemia

scholarly journals SUN-616 Poor Diagnostic Concordance Between Fasting Plasma Glucose and Glycosylated Hemoglobin in a Black South African Population

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Alisha N Wade ◽  
Nigel Crowther ◽  
F Xavier Gomez-Olive ◽  
Ryan G Wagner ◽  
Jennifer Manne-Goehler ◽  
...  
Keyword(s):  
South African ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glycosylated Hemoglobin ◽  
Kappa Statistic ◽  
African Population ◽  
South African Population ◽  
Black South African ◽  
Fasting Plasma ◽  
History Of

Abstract Background: While elevations in fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) are both recognized by the American Diabetes Association (ADA) as diagnostic of hyperglycemia, previous comparisons of these tests have demonstrated discordant individual classifications and population estimates. This may be due to additional postprandial glycemia reflected by HbA1c and, in African-descent populations, to non-glycemic factors that contribute to higher HbA1c at any given level of glycemia. We hypothesized that glycemic classifications based on FPG or HbA1c would differ in a Black South African population and investigated factors associated with discordance. Methods: 889 Black adults with previously undiagnosed diabetes, aged 40-79 years, from the population-based Health and Ageing in Africa: a Longitudinal Study of an INDEPTH Community in South Africa (HAALSI) cohort were included. Concordance between ADA FPG (normoglycemia [NG] <100 mg/dl, prediabetes [pre-DM] 100-125 mg/dl, diabetes [DM] ≥ 126 mg/dl) and HbA1c (NG <5.7%, pre-DM 5.7-6.4%, DM ≥ 6.5%) classifications was assessed using Cohen’s kappa statistic and logistic regression models were used to identify predictors of discordance. Results: Median age was 55 years (IQR 49-62) and 49.3% of the sample was male. Median glucose was 86.4 mg/dl and median HbA1c was 5.4%. Pre-DM, as defined by HbA1c, was present in 204 participants (22.9%), while FPG-defined pre-DM was present in 122 (13.7%). DM defined by HbA1c was present in 146 (16.4%), while FPG-defined DM was present in 36 (4.0%). Concordance between the two tests was poor (kappa statistic 0.18; 95%CI 0.13-0.24). Self-reported history of tuberculosis (OR 1.90, p=0.026) and higher HbA1c (OR 4.70, p<0.001) were associated with increased likelihood of discordance, whereas higher fasting glucose was associated with decreased likelihood of discordance (OR 0.58, p<0.001). There was no association between discordance and hemoglobin, HIV status, BMI, waist circumference or hip circumference. Conclusion: FPG and HbA1c exhibit poor concordance in classifying hyperglycemia in this Black South African population, with HbA1c-based definitions identifying higher prevalences of pre-DM and DM. Further work is needed to confirm whether these discrepancies are due solely to elevations in postprandial glucose. In the interim, clinicians should consider confirming elevated HbA1c concentrations with oral glucose tolerance testing, particularly in those with a history of tuberculosis, prior to making a diagnosis of DM in this population.

scholarly journals Association of Serum Uric Acid with 2-Hour Postload Glucose in Chinese with Impaired Fasting Plasma Glucose and/or HbA1c

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e67759 ◽  
Author(s):  
Hong-Qi Fan ◽  
Wei Tang ◽  
Zhi-Xiao Wang ◽  
Su-Juan Wang ◽  
Yue-Hua Qin ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Fasting Plasma

Relationship Between Fasting Plasma Glucose and Glycosylated Hemoglobin

JAMA ◽  
1999 ◽  
Vol 281 (13) ◽  
pp. 1203 ◽  
Author(s):  
Mayer B. Davidson ◽  
David L. Schriger ◽  
Anne L. Peters ◽  
Brett Lorber
Keyword(s):  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glycosylated Hemoglobin ◽  
Fasting Plasma

The Combination of Fasting Plasma Glucose and Glycosylated Hemoglobin as a Predictor for Type 2 Diabetes in Korean Adults

2009 ◽  
Vol 33 (4) ◽  
pp. 306 ◽  
Author(s):  
Chan Hee Lee ◽  
Woo Jin Chang ◽  
Hyun Hee Chung ◽  
Hyun Jung Kim ◽  
Sang Hyun Park ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glycosylated Hemoglobin ◽  
Korean Adults ◽  
Fasting Plasma

scholarly journals Determinants of Fasting Plasma Glucose and Glycosylated Hemoglobin Among Low Income Latinos with Poorly Controlled Type 2 Diabetes

2010 ◽  
Vol 13 (5) ◽  
pp. 809-817 ◽  
Author(s):  
Grace Kollannoor-Samuel ◽  
Jyoti Chhabra ◽  
Maria Luz Fernandez ◽  
Sonia Vega-López ◽  
Sofia Segura Pérez ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Low Income ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glycosylated Hemoglobin ◽  
Fasting Plasma
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